专刊题目

Brain–Computer Interfaces and Neural Network Disorders: Translational and Clinical Advances

背景描述

本专刊聚焦脑机接口（Brain–Computer Interfaces，BCI）技术与神经网络机制在各类神经系统疾病治疗中的前沿进展。随着神经调控设备硬件与解码技术的发展，BCI已从实验室走向临床，为癫痫、帕金森、中风、脊髓损伤等难治性疾病提供了全新干预手段。本特刊旨在展示推动运动功能恢复、认知康复等各类神经疾病治疗中的创新性BCI应用。我们特别关注并欢迎神经信号解码算法、闭环反馈系统设计、神经可塑性及实时自适应接口的开发等具有临床转化价值的高质量研究，一同探讨并推动BCI技术的精准化与普惠化。同时我们也欢迎跨学科团队提交涉BCI或神经（环路）网络的基础机制探索，如动物或细胞实验、单细胞或空间组学研究、影像学研究等。我们希望本特刊能够为科研人员、临床医生和产业界搭建一个知识共享平台，激发跨领域合作，从而为新一代治疗策略的探索铺路。

Our special issue focuses on the cutting-edge advances in brain-computer interfaces (BCIs) and neural network mechanisms for the treatment of various neurological disorders. With rapid developments in neuromodulation hardware and decoding techniques, BCIs have transitioned from experimental settings to clinical applications, offering novel intervention strategies for refractory conditions such as epilepsy, Parkinson's disease, stroke, and spinal cord injuries. 

This issue aims to showcase innovative BCI applications that drive motor recovery, cognitive rehabilitation, and the treatment of other neurological conditions. We are particularly interested in and welcome high-quality, clinically translatable research on neural signal decoding algorithms, the design of closed-loop feedback systems, neuroplasticity, and real-time adaptive interfaces—all pivotal to enhancing the precision and accessibility of BCI technology. We also welcome interdisciplinary teams to submit studies exploring the underlying mechanisms of BCIs and neural (circuit) networks, including animal or cellular experiments, single-cell/spatial omics research, and neuroimaging studies. We hope that this special issue will serve as a knowledge-sharing platform for researchers, clinicians, and industry professionals, fostering cross-disciplinary collaboration and paving the way for the next generation of therapeutic strategies.

关键词

脑机接口、神经网络、神经康复、神经解码、闭环系统、认知调控、运动恢复、神经技术、转化研究、神经可塑性、侵入式/非侵入式BCI

Brain–computer interfaces,  neural network, neurorehabilitation, neural decoding, closed-loop systems, cognitive modulation, motor recovery, neurotechnology, translational research, neural plasticity, invasive/non-invasive BCI

主题

• 高级信号处理与神经信号解码

Advanced signal processing and neural decoding

• 神经系统疾病的网络与分子生物学机制

Network and molecular biological mechanisms of neurological disorders

• 侵入式与非侵入式BCI

Invasive and non-invasive BCI

• 闭环BCI系统的优化与实时反馈

Real-time feedback and optimization in closed-loop BCI systems

• 基于AI（如机器学习）的个性化神经调控算法

AI-driven (e.g. machine learning) personalized neuromodulation algorithms

• 神经调控技术的临床试验及转化研究

Clinical trials and translational research in neuromodulation

• 脑机接口技术的治疗原理探索

Exploration of the therapeutic mechanisms of BCIs

稿件类型

Article, Review, Commentary, Letter

截止日期

2025年12月31日

客座专刊编辑

Guoguang Zhao

Professor

Organization: Xuanwu Hospital, Capital Medical University, China

Research area:  The clinical application and translational research of brain–computer interfaces.

Email: ggzhao@vip.sina.com

Josemir W. Sander

Professor

Organization: Department of Clinical and Experimental Epilepsy at UCL Queen Square Institute of Neurology, UK

Research area:  Managing drug-resistant epilepsy through comprehensive preoperative evaluation, epilepsy surgery, neuromodulation (e.g., VNS, DBS), and SUDEP risk-reduction protocols at leading epilepsy centers.

Email: l.sander@ucl.ac.uk

Yongzhi Shan

Professor

Organization: Xuanwu Hospital, Capital Medical University, China

Research area: The surgical management of drug-resistant epilepsy, trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia; and the diagnosis and treatment of complex neurological disorders.

Email: shanyongzhi@xwhosp.org

Yong He

Professor

Organization: Beijing Normal University, China

Research area:  Imaging connectomics.

Email: yong.he@bnu.edu.cn

投稿指南

Please submit your paper through our online submission system. All papers will be peer-reviewed. The submission deadline is December 31, 2025. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together. Research articles, review articles, letters, commentaries as well as perspectives are invited.

hLife adopts format-free submission. Format-free submission means that, provided you include everything necessary for review and using a consistent citation format, you can submit your paper without needing to worry about formatting your manuscript to meet hLife's requirements.

Please state in the cover letter that your submission is for the special section of  "Brain–Computer Interfaces and Neural Network Disorders: Translational and Clinical Advances". Article Publishing Charges (APCs) for accepted papers of hLife will be free before 2026. 

提交网站

https://www.editorialmanager.com/hlife

期刊简介

hLife 由高福院士、董晨院士和Jules A. Hoffmann教授（2011诺奖获得者）领衔，是中国科学院微生物研究所主办，中国生物工程学会，浙江大学陈廷骅大健康学院，西湖大学医学院，上海市免疫治疗创新研究院和广州霍夫曼免疫研究所联合支持，与国际出版商爱思唯尔合作的健康科学领域综合性英文期刊。

hLife 聚焦健康科学领域的前沿进展，旨在促进基础研究与临床应用的融合发展。期刊发表与医学相关各研究领域最新成果，学科领域包括（但不限于）病原生物学、流行病学、生理学、免疫学、结构生物学、疾病监测、肿瘤、药物、疫苗和健康政策等。

hLife是一本金色开放获取期刊，月刊出版；2022年成功入选“中国科技期刊卓越行动计划高起点新刊”；2023年11月正式创刊；2024年5月被DOAJ收录；2024年8月被Scopus收录。

2026年前hLife接收的稿件免收文章处理费（APC）。

期刊网址：

https://www.sciencedirect.com/journal/hlife