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- 置顶 · Nature:让实验室生活更健康快乐的十条简单原则！ Ten simple rules
- Ten simple rules towards healthier research labs 让实验室运行更加健康与快乐的十条准则 作者：Fernando T. Maestre, 2019 Maestre教授认为， 在竞争激烈的学术环境中， 快乐、善良和谦逊的力量被低估了，他坚信它们是一种有利于科学实践的变革力量 。 Maestre认为，科研工作和生活可以更好地平衡，这些原则 ...
- 【分子生物学工具网址】氨基酸密码子优化等工具网站推荐
- 密码子优化是一种通过增加靶基因的翻译效率来提高生物体内蛋白质表达水平的新技术。通常会通过避免稀有密码子，利用偏爱密码子（Preferred codons)、简化mRNA的二级结构、优化重复序列、消除限制酶切位点、调整GC含量等方法重新设计基因，以提高翻译效率，进而提高蛋白表达水平。 基因序列分析工具箱 ： http://www.deta ...
- CMI: Increased immune escape of SARS-CoV-2 Omicron variant
- Increased immune escape of the new SARS-CoV-2 varia nt of concern Omicron Jie Hu # , Pai Peng # , Xiaoxia Cao # , Kang Wu, Quan-xin Long, Juan Chen, Kai Wang, Ni Tang and Ai-long Huang* A new detected SARS-CoV-2 variant Omicron (B.1.1.529) had reported from more than 80 ...
- EMERG MICROBES INFEC: Obatoclax inhibits SARS-CoV-2 entry
- Title: Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro Published in Emerging Microbes Infections on January 06, 2022 Abstract: Coronavirus disease 2019 (COVID-19) caused by the emerging seve ...
- 新冠病毒变种B.1.640.1和B.1.640.2
- Currently, there are only 400 sequences reported for B.1.640 variant. In a similar vein to the recent split of B.1.1.529 (Omicron, 奥密克戎) into two sister sublineages it appears B.1.640 may also have a similar issue with a major group constating of the vast majority of sequences and a sma ...
- [转载]NEJM:开发广谱通用冠状病毒疫苗乃当务之急（Universal Coronavirus Vaccines）
- 2021年12月15日，《新英格兰医学杂志》（ NEJM ）在线发表美国国家过敏和传染病研究所（NIAID）所长Anthony Fauci等人文章，分析现有疫苗保护力欠佳的原因，强调开发通用冠状病毒疫苗的重要性，并指出通用疫苗开发路线。 开发通用冠状病毒疫苗乃当务之急 Universal Coronavirus Vaccines — An Urgent ...
- [转载]病毒进化学家贝德福德（Trevor Bedford）关于新冠病毒奥密克戎变异株的判断
- The novel B.1.1.529 SARS-CoV-2 variant was designated Omicron (奥秘克戎) on the 26th November 2021, following its increasing prevalence in South Africa. Harbouring more than 30 mutations in its Spike protein, the principal concerns surround Omicron’s infectivity, virulence and ability to circumv ...
- 新冠病毒变体研究Reduced neutralization of SARS-CoV-2 B.1.617 variant
- 题目Title: Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera 共同第一作者Co-first author: Jie Hu (胡杰)、Xiao-yu Wei（魏晓宇）、Jin Xiang（向进） 摘要Abstract: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory sy ...
- [转载]传染病特刊专题“ Metabolic Rewiring and Viral Infection”代谢重塑与病毒感染介绍
- 《 Frontiers in Cellular and Infection Microbiology 》 本期特刊 Metabolic Rewiring and Viral Infection 专题 简介 About this Research Topic Viruses are intracellular pathogens that rely on hijacking host resources to complete their life cycle. Specifically, upon infect ...
- 新书推荐：Fields Virology, Seventh Edition 《费氏病毒学》第7版
- NEW Book:《 Field's Virology 》7th ed Available Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of sp ...
- 学习笔记：登革病毒的血清型（DENV serotype）
- 登革病毒 的血清型 Dengue Fever (DF 登革热 ) is due to mild infection caused by one of the four serotypes of Dengue virus that may progress to a severe Dengue Hemorrhagic Fever (DHF) and subsequently to a fatal Dengue Shock Syndrome (DSS), if treatmen ...
