Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics Published:November 06, 2020 Cell Highlights Interferon response is suppressed in infected cells but activated in bystander cells EBOV represses antiviral genes and upregul ...
Identification and characterization of extrachromosomal circular DNA in maternal plasma PNAS January 21, 2020 Significance We observed the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. We found that the plasma eccDNA molecules were ...
Deep learning for inferring gene relationships from single-cell expression data PNAS December 26, 2019 Significance Accurate inference of gene interactions and causality is required for pathway reconstruction, which remains a major goal for many studies. Here, we take advantage of 2 ...
( https://www.nature.com/articles/s41594-020-0511-8?utm_source=feedburnerutm_medium=feedutm_campaign=Feed%3A+nsmb%2Frss%2Fcurrent+%28Nature+Structural+%26+Molecular+Biology+-+Issue%29) Abstract The SARS-CoV-2 non-structural protein 1 (Nsp1), also referred to as the host shut ...
The gasdermins , a protein family executing cell death and inflammation XJJ 细胞焦亡( pyroptosis) Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 Major cell death subroutines. Mammalian cells exposed ...
A single-cell atlas of the peripheral immune response in patients with severe COVID-19 Nature Medicine Published: 08 June 2020 Abstract There is an urgent need to better understand the pathophysiology of Coronavirus disease 2019 (COVID-19), the global pandemic caused by &n ...
A large-scale binding and functional map of human RNA-binding proteins Nature volume 583 , pages711–719(2020) by: XYM ENCODE是什么? ENCODE 计划全称是 The Encylopedia of DNA Elements ,意在揭开人类基因组功能元件的全面图谱。 该 ...