2025年诺贝尔生理学或医学奖因在外周免疫耐受方面的发现授予如下三位科学家: 玛丽·E·布朗科 (系统生物学研究所, 美国西雅图),弗雷德·兰斯代尔 (索诺玛生物制药公司, 美国旧金山),杉口诚 (大阪大学, 日本大阪 )
The Nobel Assembly at Karolinska Institutet has decided to award the 2025 Nobel Prize in Physiology or Medicine to:
Mary E. Brunkow(Institute for Systems Biology,Seattle, USA),Fred Ramsdell(Sonoma Biotherapeutics,San Francisco, USA),Shimon Sakaguchi(Osaka University,Osaka, Japan)
https://www.nobelprize.org/prizes/medicine/2025/press-release/
他们知道免疫系统是如何被调控的 身体强大的免疫系统必须受到调控,否则可能会攻击我们的自身器官。玛丽·E·布兰科、弗雷德·兰斯德尔和西蒙·坂口在关于外周免疫耐受性方面取得了突破性发现,这种耐受性能防止免疫系统损害身体。他们的发现为新兴研究领域奠定了基础,并推动了癌症和自身免疫性疾病等新型疗法的开发。
They understood how the immune system is kept in check
The body’s powerful immune system must be regulated, or it may attack our own organs. Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi made groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body. Their discoveries have laid the foundation for a new field of research and spurred the development of new treatments, for example for cancer and autoimmune diseases.
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