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技术、医药卫生及化学国际新闻提要(3月19日)

已有 4467 次阅读 2015-3-20 11:52 |个人分类:新科技|系统分类:博客资讯| 化学, 技术, 医药卫生, 国际新闻

技术、医药卫生及化学国际新闻提要(3月19日)

诸平

科学家发明控制光的新方法,对于下一代超快速计算机的开发至关重要——Scientists invent new way to control light, critical for next gen of super fast computing

研究人员应用最新的纳米技术,经皮给药治痤疮——

Researchers use the latest in nanotechnology and transdermal drug delivery to take on an old problem: acne

关注量子点,请浏览——

What happens when a quantum dot looks in a mirror?

用石墨烯来做点什么,关键是寻找到一种廉价的制备方法——

Finding an affordable way to use graphene is the key to its success

太阳能飞机从印度飞往缅甸——

Solar plane leaves India for next stop in MyanmarSolar-powered plane lands in Myanmar on latest leg

干细胞有望扭转2型糖尿病——Stem cells show promise for reversing type 2 diabetes

从干细胞来制造神经元,科学家有新发现——Team finds key to making neurons from stem cells

为什么有些蘑菇会光焰照人?——Some mushrooms glow, and here's why

新研究表明体温与肥胖有关——

New study suggests connection between body temperature and obesity

医学院学生发现艾滋病毒治疗后体重增加和死亡率之间有联系——

Med student finds link between weight gain after HIV treatment and mortality

堪称世界第一的抗癌药物,会使更多患者受益吗?——

World-first cancer drugs could work in larger group of patients

尿液测试有助于肾癌早发现——

Kidney cancer detected early with urine test

更多信息请浏览以下摘引内容:

Nanotechnology news

Scientists watch quantum dots 'breathe' in response to stress

Researchers at the Department of Energy's SLAC National Accelerator Laboratory watched nanoscale semiconductor crystals expand and shrink in response to powerful pulses of laser light. This ultrafast "breathing" provides new insight about how such tiny structures change shape as they start to melt – information that can help guide researchers in tailoring their use for a range of applications.

Researchers create 'nanofiber gusher'

Creating large amounts of polymer nanofibers dispersed in liquid is a challenge that has vexed researchers for years. But engineers and researchers at North Carolina State University and one of its start-up companies have now reported a method that can produce unprecedented amounts of polymer nanofibers, which have potential applications in filtration, batteries and cell scaffolding.

Researchers use the latest in nanotechnology and transdermal drug delivery to take on an old problem: acne

Acne, a scourge of adolescence, may be about to meet its ultra high-tech match. By using a combination of ultrasound, gold-covered particles and lasers, researchers from UC Santa Barbara and the private medical device company Sebacia have developed a targeted therapy that could potentially lessen the frequency and intensity of breakouts, relieving acne sufferers the discomfort and stress of dealing with severe and recurring pimples.

What happens when a quantum dot looks in a mirror?

The 2014 chemistry Nobel Prize recognized important microscopy research that enabled greatly improved spatial resolution. This innovation, resulting in nanometer resolution, was made possible by making the source (the emitter) of the illumination quite small and by moving it quite close to the object being imaged. One problem with this approach is that in such proximity, the emitter and object can interact with each other, blurring the resulting image. Now, a new JQI study has shown how to sharpen nanoscale microscopy (nanoscopy) even more by better locating the exact position of the light source.

Finding an affordable way to use graphene is the key to its success

Graphene is a remarkably strong material given it's only a single carbon-atom thick. But finding ways to do something with it – that's also affordable too – have always been a challenge.

Peering into how rechargeable lithium ion batteries function

Nanoparticle electrodes in lithium-ion batteries have both near-surface and interior contributions to their redox capacity, each with distinct rate capabilities. Using combined electron microscopy, synchrotron X-ray methods and ab initio calculations, Brookhaven National Laboratory researchers have investigated the lithiation pathways that occur in NiO electrodes. They found that the near-surface electroactive (Ni2+→Ni0) sites saturated very quickly, and then encountered unexpected difficulty in propagating the phase transition into the electrode (referred to as a "shrinking-core" mode).

Technology news

Scientist hopes vest will broaden range of human senses

Neuroscientist David Eagleman hopes that one day a special piece of clothing he has designed will let the deaf "hear" and allow wearers to sense what is happening online without looking at a computer.

Hidden benefits of electric vehicles revealed

Electric vehicles are cool, research shows. Literally. A study in this week's Scientific Reports by researchers at Michigan State University (MSU) and in China add more fuel to the already hot debate about whether electric vehicles are more environmentally friendly than conventional vehicles by uncovering two hidden benefits.

Robotic materials: Changing with the world around them

Prosthetics with a realistic sense of touch. Bridges that detect and repair their own damage. Vehicles with camouflaging capabilities.

Solar plane leaves India for next stop in Myanmar

A solar-powered airplane on a historic round-the-world journey took off Thursday from the northern Indian town of Varanasi and was headed for its next stop in Myanmar.

Google exec says immigration changes would help economy

The executive chairman at Google urged Congress on Wednesday to increase the number of high-skilled work visas made available to foreigners and to deal with other immigration issues later on.

China boosts fleet of electric, hybrid vehicles

Chinese authorities have announced plans to boost the number of electric, hybrid and other alternative fuel-powered vehicles used for public transportation, while sales of such cars for private use have spiked in recent months.

US turns to rewards in hunt for overseas cyber criminals

The FBI considers Evgeniy Bogachev one of the world's most prolific and brilliant cyber criminals, slapping his photos—bald, beefy-faced and smiling faintly—on "Wanted" fliers posted online. The Russian would be an ideal target for prosecution—if only the Justice Department could find him.

Yahoo shutting down China office in latest cost-cutting move (Update)

Yahoo is closing its research and development center in China as CEO Marissa Mayer tries to placate shareholders pressuring the Internet company to cut costs while it struggles to bring in more revenue.

Amazon.com introduces one-hour delivery to Baltimore, Miami

Amazon.com Inc. is expanding its one-hour delivery Prime Now service for household products to Baltimore and Miami.

Big in Asia, Line app hopes cute factor will win worldwide

Mickey Mouse, Hello Kitty: Move over. And make way for laidback Brown bear and his irrepressible girlfriend Cony the bunny.

Sensing devices for people suffering with anxiety

Imagine technology that is good enough to wear and safe enough to eat!

After years in shadows, France wants legal data monitoring (Update)

France's government pressed Thursday to legalize broad surveillance of terrorism suspects with a measure that would allow intelligence services to vacuum up metadata in hopes of preventing imminent attacks.

How to tackle cyber crime before people even know they're a victim

An estimated A$75,000 is lost by Australians everyday to online fraud, according to the Australian Competition and Consumer Commission (ACCC).

Gamification harnesses the power of games to motivate

Walk through any public area and you'll see people glued to their phones, playing mobile games like Game of War and Candy Crush Saga. They aren't alone. 59% of Americans play video games, and contrary to stereotypes, 48% of gamers are women. The US$100 billion video game industry is among the least-appreciated business phenomena in the world today.

Rubber research may extend life of amphibious assault vehicle

The U.S. Naval Research Laboratory (NRL) has found that some types of rubber provide corrosion protection—and potentially better ballistic protection—for amphibious assault vehicles (AAVs). This is important to the U.S. Marine Corps (USMC) as they look to extend the AAV, introduced in 1972, through 2035. "Innovative sustainment concepts, like those NRL is investigating, enable us to avoid the cost of new design, development, and production of new components," says Tim Bergland of the USMC Advanced Amphibious Assault (AAA) office.

Judge OKs $10 million settlement in Target data breach

A Minnesota judge has endorsed a settlement in which Target Corp. will pay $10 million to settle a class-action lawsuit over a massive data breach in 2013.

Angry Birds wing it, go 3D

Finnish entertainment company Rovio, creator of the hugely popular Angry Birds brand, on Thursday said it was betting on a new 3D release to swoop back from a massive loss in profit.

Solar-powered plane lands in Myanmar on latest leg

A solar-powered plane landed in Myanmar on Thursday night, the latest leg of a round-the-world trip aimed at highlighting clean energy.

TAG Heuer to partner with Google, Intel to create smartwatch (Update)

Luxury Swiss watchmaker TAG Heuer announced Thursday it was joining forces with technology behemoths Google and Intel to develop a smartwatch that can compete with the new Apple Watch.

Emerging nations see benefits, problems with Internet

People in emerging economies see the Internet as a good thing for education and the economy, but worry about its impact on morality, a global survey showed Thursday.

Nearly all fuel in Fukushima reactor has melted, says TEPCO

New tests show almost all of the fuel inside one of the Fukushima plant's reactors has melted, its operator said Thursday, the latest step in the clean up after Japan's worst ever nuclear crisis.

Cyber attackers leaving warning 'messages': NSA chief

Attackers hacking into American computer networks appear to be leaving "cyber fingerprints" to send a message that critical systems are vulnerable, the top US cyber-warrior said Thursday.

Tesla updating Model S to ease range anxiety, improve safety

Tesla Motors is updating its Model S electric car to help ease drivers' worries about running out of battery charge—and is hinting that in the future drivers can take their hands off the wheel altogether.

New rooftops in France to go green

Rooftops on new buildings built in commercial zones in France must either be partially covered in plants or solar panels, under a law approved on Thursday.

US allows Amazon to test drones

US aviation officials announced Thursday they will allow online giant Amazon to carry out testing for its drone program which could be used for quick deliveries.

Ferguson Facebook case part of debate about online threats

A Washington state man faces sentencing for posting threats on Facebook against a former Ferguson, Missouri, police officer who fatally shot a young black man—a case that is part of a broader legal debate over when social media rants go beyond hyperbole and become criminal acts.

Power companies unprepared for hacking attacks

Researchers are recommending that Norwegian power distribution companies should carry out more regular contingency exercises to prepare themselves for hacking attacks. If they don't, they won't be equipped to identify and deal with crisis situations.

Apple stock starts trading as part of Dow today

The world's most valuable company is now a member of the Dow Jones industrial average.

Atlas of thoughts

Using a computer game, a research group at Aarhus University has found a way to gain deeper insight into the human thought process. The results have amazed the research director, who has discovered a kind of 'atlas of thoughts.' And that is not all. The group can also reveal which gender is best at solving quantum problems.

Test security now means checking social media for cheaters

For the organizations that give standardized tests, it's a common—and common-sense—security measure.

Streaming revenue edges out CDs in US

Streaming has topped CD sales in revenue for the first time in the United States as music listeners flock to on-demand services and Internet radio, industry figures showed.

Monica Lewinsky takes cyber-bully fight to TED

Monica Lewinsky on Thursday took her freshly launched fight against cyber-bullying to a premier TED gathering known for attracting Internet titans, celebrities and others influencing modern culture.

Canada auditor general lost data: report

The office of Canada's auditor general lost 120 USB drives, or one in five entrusted to staff last year, possibly containing sensitive information, a local newspaper reported Thursday.

Medicine & Health news

New drug for Crohn's disease shows early promise

(HealthDay)—An experimental drug may quickly quash symptoms of the digestive disorder Crohn's disease—at least for the short term, an early clinical trial finds.

Scientists grow 'mini-lungs' to aid the study of cystic fibrosis

Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.

Aggressively pursuing higher social status may exact a toll on health

Bad news for relentless power-seekers the likes of Frank Underwood on House of Cards: Climbing the ladder of social status through aggressive, competitive striving might shorten your life as a result of increased vulnerability to cardiovascular disease. That's according to new research by psychologist Timothy W. Smith and colleagues at the University of Utah. And good news for successful types who are friendlier: Attaining higher social status as the result of prestige and freely given respect may have protective effects, the researchers found.

Our eyes multi-task even when we don't want them to, researchers find

Our eyes are drawn to several dimensions of an object—such as color, texture, and luminance—even when we need to focus on only one of them, researchers at New York University and the University of Pennsylvania have found. The study, which appears in the journal Current Biology, points to the ability of our visual system to integrate multiple components of an item while underscoring the difficulty we have in focusing on a particular aspect of it.

Stem cells show promise for reversing type 2 diabetes

Scientists at the University of British Columbia and BetaLogics, part of Janssen Research & Development, LLC have shown for the first time that Type 2 diabetes can be effectively treated with a combination of specially-cultured stem cells and conventional diabetes drugs.

Team finds key to making neurons from stem cells

A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.

Even at a molecular level, taking it slow helps us cope with stress

Scientists at the University of California, Berkeley, have identified a new molecular pathway critical to aging, and confirmed that the process can be manipulated to help make old blood like new again.

Altering brain chemistry makes us more sensitive to inequality

What if there were a pill that made you more compassionate and more likely to give spare change to someone less fortunate? UC Berkeley scientists have taken a big step in that direction.

'Missing culprit' in heart failure identified

Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as "the long-sought culprit" in the mystery behind a cell-signaling breakdown that triggers heart failure. The condition, which affects nearly 6 million Americans and 23 million people worldwide, is marked by progressive weakening and stiffening of the heart muscle and the organ's gradual loss of blood-pumping ability.

Standardized packaging with large graphic health warnings encouraged more thoughts about quitting

Introduction of standardised packaging for tobacco products in Australia prompted more smokers to think about quitting and to attempt to quit, show findings of surveys of adults smokers published in Tobacco Control.

Dramatic rise expected in adults living with cystic fibrosis

The number of people living with cystic fibrosis into adulthood is expected to increase dramatically by 2025, prompting calls for the development of adult cystic fibrosis services to meet the demand.

Melatonin can help you get a good night's sleep in a noisy environment

Using melatonin could provide more and better quality sleep compared to using an eye mask and earplugs in a simulated noisy and illuminated environment, according to research published in open access journal Critical Care. This study was carried out on healthy subjects but could have future implications for intensive care unit (ICU) patients.

Study: Fast-food curb did not cut obesity rate in South LA

A much-hailed law that restricted the opening of new stand-alone fast-food restaurants in one of the poorest sections of Los Angeles did not curb obesity or improve diets, a new study found.

Targeted drug doubles progression free survival in Hodgkin lymphoma

A phase 3 trial of brentuximab vedotin (BV), the first new drug for Hodgkin lymphoma in over 30 years, shows that adults with hard-to-treat Hodgkin lymphoma given BV immediately after stem cell transplant survived without the disease progressing for twice as long as those given placebo (43 months vs 24 months).

Bill Gates calls for 'germ games' instead of war games

Bill Gates opened a mock Ebola field hospital at the prestigious TED Conference as part of a call to be battle-ready for a deadly global epidemic.

New insight into tackling poor oral health in children around the globe

A new research project from the University of Copenhagen has established an effective model for the fight against the escalating burden of tooth decay among children in Asia. The model is an important tool in breaking the social inequity in oral health of children.

Excessive vitamin intake in pregnant rats impacts food choices in offspring

A research group at the Department of Nutritional Sciences at the University of Toronto, Faculty of Medicine has been using a rat model to see how maternal intake of above-requirement vitamins (A, D, E, and K) impact offspring's brain development and behaviour. Some of their findings were published today in the journal Applied Physiology, Nutrition, and Metabolism.

Breast implants could become safer thanks to cell-friendly surface

Scientists at The University of Manchester have created an enhanced surface for silicone breast implants which could reduce complications and make them less likely to be rejected by the body.

Researchers find towels to be a top source of cross contamination within the kitchen

Although only 9 percent of reported foodborne illness outbreaks occur in the home, scientists estimate the actual number of incidents is much higher. Research shows a leading cause of cross contamination within the home is actually an object associated with cleaning, the kitchen towel.

New study suggests connection between body temperature and obesity

A new study suggests that a biological inability to create sufficient core body heat could be linked to the obesity epidemic. "Evidence of a diurnal thermogenic handicap in obesity" is featured in this year's second issue of Chronobiology International.

Depressive thoughts may have a negative effect on working memory

A new study in the journal Cognition and Emotion illustrates the link between reduced working memory capacity and dysphoria, a significant and prolonged depressed mood related to clinical depression.

Migrant dentists contribute to brain drain for developing and poorer countries

Dentists migrate to Australia seeking "better opportunities" and "adventure" but they also contribute towards brain drain for developing and poorer countries.

Controlling stress responses

Think finals are stressful? Try being chased by a lion.

Examining water-borne parasites that cause intestinal schistosomiasis

Water is essential for life on Earth. It is crucial for environmental and human health, necessary for food and energy security, and indispensable for continued urbanization and industry. One in nine people lacks access to safe water, but what does this mean?

Measuring health care

When Oregon voted in 2008 to use a lottery to determine which low-income adults to add to its Medicaid rolls, Stephen Colbert mocked the effort as "gambling for health insurance."

Research team defines genetic subtypes of asthma

A Yale-led analysis of gene expression in asthma patients identified three major clusters of the disease. The finding could lead to a personalized approach to asthma management.

Med student finds link between weight gain after HIV treatment and mortality

Bianca Yuh, a third-year student at Yale School of Medicine, spent last summer working on her thesis with the Veterans Aging Cohort Study, a key source of data on HIV-infected veterans. She was interested in investigating factors that determine positive and negative outcomes for older people with HIV infection after they receive treatment. Her findings, published March 11 in Clinical Infectious Diseases, suggest an easy intervention that requires no additional medication or diagnostic evaluation.

Pediatrician gives tips for dealing with diaper rash

Diaper rash may not be a serious condition, but it can be extremely painful. It is common and causes concern for many parents trying to comfort their child.

Spinal cord neurons that control pain and itch

The spinal cord transmits pain signals to the brain, where they are consciously perceived. But not all the impulses arrive at their destination: Certain neurons act as checkpoints and determine whether a pain signal is relayed or not. Researchers from UZH identified these neurons and their connections. Moreover, they developed means to specifically activate these neurons, which reduces not only pain – but astonishingly also alleviates itch.

Scientists trace genomic evolution of high-risk leukemia

By genomic sequencing of leukemia cells from relapsed patients at different stages, scientists have discovered key details of how acute lymphoblastic leukemia (ALL) cells mutate to survive chemotherapy. These mutations enable the cells to proliferate, causing relapse and often death.

New hopes for rheumatic fever vaccination

A new vaccine to combat the debilitating disease caused by rheumatic fever may soon become a reality, saving hundreds of thousands of deaths from preventable heart disease around the world each year.

Pneumococcal vaccine success in New Zealand children

Infectious disease experts are this week calling New Zealand's pneumococcal vaccination schedule an unequivocal success.

Chemical advance supports treatment Alzheimer's disease

Researchers at the University of Liverpool and Victoria University of Wellington have made a significant step forward in the search for a treatment for Alzheimer's disease.

Are doctors following best practice when prescribing antipsychotic meds to kids?

There's been a lot of attention in the media about the number of children taking antipsychotic and other psychiatric medications. The assumption behind most of these stories is that these drugs are being overprescribed, and given to children with minor behavioral issues. A recent story in a European newspaper about the increased use of ADHD medications, for example, was headlined "Zombie Generation." Yet the reality is there's very little data to tell us the degree to which these medications are being used appropriately or not.

World-first cancer drugs could work in larger group of patients

A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumours with another type of genetic fault, a new study suggests.

Kidney cancer detected early with urine test

If kidney cancer is diagnosed early—before it spreads—80 percent of patients survive. However, finding it early has been among the disease's greatest challenges.

Effect of smoking, alcohol on feeding tube duration in head/neck cancer patients

Current smoking and heavy alcohol consumption appear to be risk factors for prolonged use of a gastrostomy tube (GT, feeding tube) in patients with head and neck cancer undergoing radiotherapy or chemoradiotherapy, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery.

Racial, ethnic differences in picking surgeons, hospitals for breast cancer care

Black and Hispanic women with breast cancer were less likely to pick their surgeon and the hospital for treatment based on reputation compared with white women, suggesting minority patients may rely more on physician referrals and health plans in those decisions, according to a study published online by JAMA Oncology.

Vitamin D helps immune cells prevent atherosclerosis and diabetes

In recent years, a deficiency of vitamin D has been linked to type 2 diabetes and heart disease, two illnesses that commonly occur together and are the most common cause of illness and death in Western countries. Both disorders are rooted in chronic inflammation, which leads to insulin resistance and the buildup of artery-clogging plaque.

Chromosome shattering may be a hidden cause of birth defects

The human genome can be very forgiving. When children inherit chromosomes from their parents, some minor genetic changes frequently occur with few, if any, consequences. One exception, as researchers report in the March 19 issue of the American Journal of Human Genetics, is chromosomal shattering, termed chromothripsis, which the authors found in healthy mothers who had each given birth to a severely affected child. The findings could have important implications for genetic testing and issues related to infertility.

Medical expansion has led people worldwide to feel less healthy

Across much of the Western world, 25 years of expansion of the medical system has actually led to people feeling less healthy over time, a new study has found.

What effect does music TV have on the sexual behavior of teenage boys and girls?

There is no doubt that teenage boys and girls are swayed and shaped by music TV. For example, sexually active youth of both genders, after watching music TV, think their peers are sexually active, too. Moreover, when girls and boys perceive males in music videos as being sexually active, it makes boys watch more music TV, and girls watch less. These are some of the surprising findings from a study conducted at the Catholic University of Leuven in Belgium, published in Springer's journal Sex Roles. The results question the frequently reported blanket influence of the mass media on teenagers' sexual behavior.

Using tablets to screen new, expecting moms for perinatal depression

Pregnant women and new mothers at one central Illinois public health clinic will soon receive depression screenings using mobile health - also called mHealth - technology.

Water pipes can be more harmful than cigarettes: experts

World health experts warned Thursday that smoking water pipes, long popular in the Middle East and North Africa and with a growing fan base elsewhere, can be more harmful than cigarettes.

Cancer therapy 'tumor sanctuaries' and the breeding ground of resistance

Tumors acquiring resistance is one of the major barriers to successful cancer therapy. Feng Fu, Sebastian Bonhoeffer (ETH Zurich) and their collaborator Martin Nowak (Harvard) use mathematical models to characterize how important aspects of tumor microenvironment can impair the efficacy of targeted cancer therapies.

The dissemination of staph infections in hospitals

Wireless sensors recording human interactions explain the transmission of germs, such as MRSA, in hospitals, according to research by Thomas Obadia and colleagues.

Fewer multiple births could reduce autism risk in ART children

In a paper published online today, scientists report that the incidence of diagnosed autism was twice as high for assisted reproductive technology (ART) as non-ART births among the nearly 6 million children in their study, born in California from 1997 through 2007. However, much of the association between ART and autism was explained by age and education of the mother as well as adverse perinatal outcomes, especially multiple births. After accounting for these factors, the study showed an elevated risk only for mothers ages 20-34.

Total body iron balance: Liver MRI better than biopsy

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have demonstrated that MR imaging of the liver is more accurate than liver biopsy in determining total body iron balance in patients with sickle cell disease and other disorders requiring blood transfusion therapy. This discovery follows the researchers earlier work in pioneering techniques to use MRI to noninvasively measure liver iron. Their study has been published online in Magnetic Resonance Imaging.

Study finds being near greened vacant lots lowers heart rates

Greening vacant lots may be associated with biologic reductions in stress, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Residents who walked near newly greened vacant lots had significantly lower heart rates compared to walking near a blighted, or neglected, vacant lot.

Slowed growth could signal Crohn's disease in kids

(HealthDay)—A lag in growth could be a sign that a child might suffer from undiagnosed inflammatory bowel disease (IBD), especially Crohn's disease, one pediatric doctor says.

Joblessness triples odds for depression in young adults

(HealthDay)—Unemployed young adults have three times the risk of depression compared to their employed peers, a new study finds.

Strength training may cut type 2 diabetes risk in Asian workers

(HealthDay)—Strength training may help cut the risk of incident type 2 diabetes in a working-age Asian population, according to a study published online March 2 in the Journal of Diabetes Investigation.

In-clinic health coaching improves cardiometabolic health

(HealthDay)—Health coaching by medical assistants can help improve hemoglobin A1c and low-density lipoprotein (LDL) cholesterol control, according to a study published in the March/April issue of the Annals of Family Medicine.

Patient status at ICU discharge, not timing, predicts survival

(HealthDay)—For patients discharged from the intensive care unit (ICU), patient status, particularly the presence of limitations of medical therapy (LOMT) orders, strongly predicts mortality, according to a study published online March 2 in the American Journal of Respiratory and Critical Care Medicine.

Higher fitness level tied to lower diabetes risk

(HealthDay)—Higher cardio-respiratory fitness is associated with a lower risk of incident diabetes, regardless of demographic characteristics, according to a study published online March 12 in Diabetes Care.

New assessment tool helps predict risk of cognitive decline

(HealthDay)—A new assessment tool may be able to predict risk of mild cognitive impairment (MCI) in older adults, according to a study published online March 18 in Neurology.

CDC: Patients frequently choose ERs further from home

(HealthDay)—Less than half of all emergency department visits occur at the emergency department closest to a patient's home, according to a March data brief published by the U.S. Center for Disease Control and Prevention's National Center for Health Statistics (NCHS).

Expert urges action to eradicate yaws, tropical disease

Half a century ago, a concentrated global effort nearly wiped a disfiguring tropical disease from the face of the earth. Now, says Case Western Reserve's James W. Kazura, MD, it's time to complete the work.

Live donor liver transplantation found safe and effective for acute liver failure

When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly. New research published in the American Journal of Transplantation indicates that emergency evaluations of living liver donors can be conducted safely to allow acute liver failure patients to undergo transplantation before their condition worsens.

New tobacco atlas details scale, harms of tobacco epidemic

The Tobacco Atlas, Fifth Edition ("The Atlas"), and its companion mobile app and website TobaccoAtlas.org, were unveiled today by the American Cancer Society and World Lung Foundation at the 16th World Conference on Tobacco or Health. The Atlas graphically details the scale of the tobacco epidemic; the harmful influence of tobacco on health, poverty, social justice, and the environment; the progress being made in tobacco control; and the latest products and tactics being used by the industry to protect its profits and delay and derail tobacco control.

Poll: Public unaware Obama's health law is again in jeopardy

With a decision due by summer in a Supreme Court case that could unravel President Barack Obama's health care law, a new poll finds many Americans have heard nothing about the case.

Study uncovers predictors of chronic kidney disease worsening in children and adolescents

Study results published today in the National Kidney Foundation's American Journal of Kidney Diseases provide new insights into why a child's chronic kidney disease (CKD) may worsen to kidney failure. Among nearly 500 children and adolescents with mild to moderate CKD, researchers identified factors, such as high blood pressure, protein loss from the kidneys, and anemia, that predicted disease worsening but that could be treated to ideally change the course of the disease. Pediatric nephrologist Bradley Warady, MD, of Children's Mercy Kansas City is a co-Principal Investigator of the NIH-funded Chronic Kidney Disease in Children (CKiD) study, the largest study of its kind ever conducted in North America.

Stress, anxiety and depression among custodial grandparents

New research published in Journal of Family Studies this month reveals that grandparents who care for grandchildren with abnormal emotional and hyperactive symptoms are more likely to experience lower levels of life satisfaction.

Insuring undocumented residents could help solve multiple US health care challenges

Latinos are the largest ethnic minority group in the United States, and it's expected that by 2050 they will comprise almost 30 percent of the U.S. population. Yet they are also the most underserved by health care and health insurance providers.

Mechanobiology provides insight into disease and healing processes

Researchers in Singapore are gaining further insight into how the mechanical environment of cells drives fundamental cellular processes such as motility, growth and survival. These processes are integral to many clinical challenges, from cancer prognosis to wound healing and skin repair.

Text message reminders boost breast cancer screening attendance

Women who received a text message reminding them about their breast cancer screening appointment were 20 per cent more likely to attend than those who were not texted, according to a study published in the British Journal of Cancer today (Thursday).

New knowledge strengthens risk assessment of chemical cocktails in food

Denmark's largest research project on chemical cocktail effects in food, spearheaded by the National Food Institute, Technical University of Denmark, has just been completed. It has established that even small doses of chemicals can have significant negative effects if they are present together. A reliable method for calculating the effects of chemical cocktails has been developed in the project. The project has also shown a need for limiting the Danish population's exposure to certain substances.

High rate of strep bacteria bugging kiwi kids

More than half of healthy New Zealand pre-school children are carriers of Staphylococcus aureus, and one in six hosts Streptococcus pyogenes in their nostrils, throat or crook of the arm, according to new research from the Growing Up in New Zealand study.

New research investigates potential probiotic benefits of a pear-enriched diet

A new in vitro (test tube) study, "Dietary functional benefits of Bartlett and Starkrimson pears for potential management of hyperglycemia, hypertension and ulcer bacteria Helicobacter pylori while supporting beneficial probiotic bacterial response," was published in the March issue of Food Research International.

Ebola-hit Sierra Leone to lock down 2.5 million people (Update)

Sierra Leone said Thursday it will confine around 2.5 million people to their homes across the capital and in the north in a three-day shutdown aimed at stemming the Ebola epidemic.

MDC researchers uncover regulatory network in the kidney

The kidney carries out vital functions by continuously filtering the blood and excreting waste products into the urine. This is achieved by a complex system of tubules which transports the urine and regulates its composition. PhD student Annekatrin Aue, Dr. Christian Hinze and Professor Kai Schmidt-Ott of the Max Delbrück Center for Molecular Medicine (MDC) have now discovered how parts of these kidney tubules establish an inner space (lumen) and form a tight barrier against adjacent structures. The epithelial cells which line the tubules coordinate these processes through a novel molecular signaling pathway.

Researchers tweak the immune system to target cells bearing tumor antigens

Researchers at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité - Universitätsmedizin Berlin, Campus Berlin-Buch, have succeeded in generating cells of the immune system to specifically target and destroy cancer cells. The research findings of Matthias Obenaus, Professor Thomas Blankenstein (MDC and Charité), Dr. Matthias Leisegang (MDC) and Professor Wolfgang Uckert (Humboldt-Universität zu Berlin and MDC) as well as Professor Dolores Schendel (Medigene AG, Planegg/Martinsried) have now been published in Nature Biotechnology online.

Physician practices need help to adopt new payment models, study finds

Physician practices are engaging in new health care payment models intended to improve quality and reduce costs, but are finding that they need help with successfully managing increasing amounts of data and figuring out how to respond to the diversity of programs and quality metrics from different payers, according to a new joint study by the RAND Corporation and the American Medical Association.

Impact of parents' military deployment on children's safety and mental health

A recent study published in the Journal of the American Academy of Child and Adolescent Psychiatry reports that following military parents' return from combat deployment, their children show increased visits for mental healthcare, physical injury, and child maltreatment consults, compared to children whose parents have not been deployed. The same types of healthcare visits were also found to be significantly higher for children of combat-injured parents.

Researchers find topical TXA in total joint replacement lowers blood transfusion use

Orthopedic surgeons from The Miriam Hospital have conducted a cost-benefit analysis of topical tranexamic acid (TXA) in primary total hip and knee arthroplasty patients that revealed a 12 percent transfusion rate reduction - from 17.5 percent to 5.5 percent - with no significant difference in complication rates. In addition to reducing the risk for postoperative bleeding and transfusion following total joint replacement, use of topical TXA enabled approximately 9.3 percent more patients to be discharged to home rather than to a skilled nursing facility. The study and its findings have been published in print in The Journal of Arthroplasty.

Immigrants are usually in better health than native Canadians... at least when they arrive

Research has shown that the health of immigrants is generally better than that of citizens of their host country, at least on their arrival and for some time afterwards. But a team of researchers in Montreal has found that this is not true of all groups of immigrants; children and older people, for example, may be exceptions.

New PET image analysis technique tracks amyloid changes with greater power

Researchers from Banner Alzheimer's Institute (BAI) have developed a new brain image analysis method to better track the progression of beta-amyloid plaque deposition, a characteristic brain abnormality in Alzheimer's disease, according to a study published in the March issue of the Journal of Nuclear Medicine. Investigators also believe this new approach may make it easier to evaluate investigational anti-amyloid treatments in clinical trials.

S.Africa HIV+ women forced to sterilise: rights groups

Doctors at some public hospitals in South Africa have allegedly coerced dozens of HIV-positive women to undergo sterilisation over the past three decades, rights groups said Thursday.

Campaign hopes for Tasmanian tobacco-free generation law

Campaigners for a proposed law to ban tobacco sales to anyone born after 2000 said Thursday they were hopeful the bill will be adopted by an Australian state's parliament next week.

Study reports excellent outcomes among HIV+ kidney transplant recipients

HIV+ kidney transplant recipients who are not infected with hepatitis C virus (HCV) have similar kidney and patient survival rates as HIV- recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings suggest that excellent outcomes can be achieved among HIV+ kidney transplant recipients.

ACC releases latest training recs for cardiology fellows

(HealthDay)—The newest iteration of the Core Cardiovascular Training Statement, COCATS 4, updating training recommendations for cardiovascular fellows, has been released by the American College of Cardiology.

Officials urge meningitis shots at University of Oregon

Public health officials issued a plea to parents of University of Oregon students to get their children vaccinated against meningitis after a sixth student has been found infected with the bacteria that can cause the potentially fatal disease.

Streamlined 'military' work flow means more patient appointments and fewer return visits

Both patients and physicians may benefit from a "work flow" system developed at military medical facilities and tested at a Johns Hopkins Kimmel Cancer Center clinic, according to results of an efficiency study.

Chemistry news

Metal oxidation controlled by atomic surface steps

Rust never sleeps. Whether a reference to the 1979 Neil Young album or a product designed to protect metal surfaces, the phrase invokes the idea that corrosion from oxidation—the more general chemical name for rust and other reactions of metal with oxygen—is an inevitable, persistent process. But a new study performed at the Center for Functional Nanomaterials (CFN) at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory reveals that certain features of metal surfaces can stop the process of oxidation in its tracks.

Synthesis and characterization of an important intermediate for biocatalysts

(Phys.org)—Cytochrome P450 (CYP) is sometimes referred to as the "Rosetta Stone" of iron-containing oxygenases, because of its ubiquity as a biocatalyst for various reactions, including drug metabolism and synthesis of biological molecules. Importantly, CYP catalyzes carbon-hydrogen hydroxylation reactions, cleaving some of the most difficult carbon-hydrogen bonding structures. While CYP is well studied, scientists are eager to understand the ferryl intermediates formed during hydroxylation in an effort to fine-tune catalytic reactions as well as seek out other biocatalysts to react with carbon-hydrogen bonds that are typically unreactive.

The taming of the shrew: Scientists decipher the spectrum of CH5+ for the first time

For the first time ever, a team of scientist from the University of Cologne headed by Professor Stephan Schlemmer succeeded in understanding the spectrum of the highly fluxional molecule CH5+. This insight, gained in collaboration with a Japanese colleague, was made possible by the extreme cooling of this enigmatic molecule and a highly accurate measurement of its vibrational transitions. The results will be presented on March 20, 2015 in Science magazine.

Model captures new dynamics of corrosion damage

University of Nebraska-Lincoln engineers have become the first to develop a model that literally looks beyond the surface of corrosion to better predict its spread.

Rare-earth innovation to improve nylon manufacturing

The Critical Materials Institute, a U.S. Department of Energy Innovation Hub, has created a new chemical process that makes use of the widely available rare-earth metal cerium to improve the manufacture of nylon.

Study holds great promise for advancing sustainable energy

New research published by Rutgers University chemists has documented significant progress confronting one of the main challenges inhibiting widespread utilization of sustainable power: Creating a cost-effective process to store energy so it can be used later.

The purification and characterization of ATP synthase complexes from the mitochondria of four fungal species

ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. We have isolated the machines from four fungal species, compared their stabilities and identified the proteins from which they are constructed.

New composite material promises to displace imports from outside Europe

High-end furniture at low cost might soon become reality thanks to a new composite material developed under the LIMOWOOD project.

Click! That's how modern chemistry bonds nanoparticles to a substrate

Nanoparticles of various types can be quickly and permanently bonded to a solid substrate, if one of the most effective methods of synthesis, click chemistry, is used for this purpose. The novel method has been presented by a team of researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences, Warsaw, Poland.

Video: Why 'hypoallergenic' isn't a thing

It's a simple claim made on thousands of personal care products for adults and kids: hypoallergenic. But what does that actually mean? Turns out, it can mean whatever manufacturers want it to mean, and that can leave you feeling itchy.



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