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中国农业大学秦峰团队报道一个优良抗旱玉米种质的基因组组装与遗传解剖。2023年2月20日，《自然—遗传学》杂志在线发表了这项成果。

研究人员报告了一个突出的抗旱基因型CIMBL55的高质量基因组组装。基因组和遗传变异分析表明，CIMBL55中发现了108个先前鉴定的抗旱候选基因中的65个有利等位基因，这可能构成了CIMBL55优异抗旱性的遗传基础。值得注意的是，编码一种reticulon样蛋白的ZmRtn16被发现通过促进液泡H⁺-ATP酶活性来促进抗旱性，这突出了液泡质子泵在玉米抗旱性中的作用。组装的CIMBL55基因组为植物抗旱性的遗传解剖和改进提供了基础，也为全球粮食安全提供了支持。

据介绍，在气候变化的背景下，干旱是影响作物生产的最限制性因素之一。玉米作为主要作物，极易受到水分亏缺的影响，产量损失严重。抗旱种质的鉴定和利用是该性状遗传改良的关键。

附：英文原文

Title: Genome assembly and genetic dissection of a prominent drought-resistant maize germplasm

Author: Tian, Tian, Wang, Shuhui, Yang, Shiping, Yang, Zhirui, Liu, Shengxue, Wang, Yijie, Gao, Huajian, Zhang, Shuaisong, Yang, Xiaohong, Jiang, Caifu, Qin, Feng

Issue&Volume: 2023-02-20

Abstract: In the context of climate change, drought is one of the most limiting factors that influence crop production. Maize, as a major crop, is highly vulnerable to water deficit, which causes significant yield loss. Thus, identification and utilization of drought-resistant germplasm are crucial for the genetic improvement of the trait. Here we report on a high-quality genome assembly of a prominent drought-resistant genotype, CIMBL55. Genomic and genetic variation analyses revealed that 65 favorable alleles of 108 previously identified drought-resistant candidate genes were found in CIMBL55, which may constitute the genetic basis for its excellent drought resistance. Notably, ZmRtn16, encoding a reticulon-like protein, was found to contribute to drought resistance by facilitating the vacuole H+-ATPase activity, which highlights the role of vacuole proton pumps in maize drought resistance. The assembled CIMBL55 genome provided a basis for genetic dissection and improvement of plant drought resistance, in support of global food security.

DOI: 10.1038/s41588-023-01297-y

Source: https://www.nature.com/articles/s41588-023-01297-y

Nature Genetics：《自然—遗传学》，创刊于1992年。隶属于施普林格·自然出版集团，最新IF：41.307
官方网址：https://www.nature.com/ng/
投稿链接：https://mts-ng.nature.com/cgi-bin/main.plex