小柯机器人

科学家绘制出欧洲玉米基因组图谱
2020-07-29 22:42

德国慕尼黑工业大学Klaus F. X. Mayer、Chris-Carolin Schön等研究人员合作绘制出欧洲玉米基因组图谱。这一研究成果于2020年7月27日在线发表在《自然—遗传学》杂志上。

研究人员报道了四个欧洲玉米品系的从头基因组序列组装。与两个美国玉米品系的比较分析说明了不同种质之间的明显差异。虽然总体的基因注释仅揭示了一定程度的基因组差异,但全基因组比对描述了核心和非必须的基因组,而异色结节和直系同源的长末端重复逆转录转座子分析揭示了玉米基因组的动态。
 
这些高质量基因组序列能够与玉米全基因组互补,从而为研究玉米在基因组规模上的改良以及增强现代杂交育种提供了重要的工具。
 
据悉,玉米的多样性是现代杂种模式和杂交育种的基础。在历史上,美国农民利用这种变异性,利用杂交种建立了如今高产的玉米自交系。
 
附:英文原文

Title: European maize genomes highlight intraspecies variation in repeat and gene content

Author: Georg Haberer, Nadia Kamal, Eva Bauer, Heidrun Gundlach, Iris Fischer, Michael A. Seidel, Manuel Spannagl, Caroline Marcon, Alevtina Ruban, Claude Urbany, Adnane Nemri, Frank Hochholdinger, Milena Ouzunova, Andreas Houben, Chris-Carolin Schn, Klaus F. X. Mayer

Issue&Volume: 2020-07-27

Abstract: The diversity of maize (Zea mays) is the backbone of modern heterotic patterns and hybrid breeding. Historically, US farmers exploited this variability to establish today’s highly productive Corn Belt inbred lines. Here, we report de novo genome sequences of four European flint lines assembled to pseudomolecules with scaffold N50 ranging from 6.1 to 10.4Mb. Comparative analyses with two US Corn Belt lines explains the pronounced differences between both germplasms. While overall syntenic order and consolidated gene annotations reveal only moderate pangenomic differences, whole-genome alignments delineating the core and dispensable genome, and the analysis of heterochromatic knobs and orthologous long terminal repeat retrotransposons unveil the dynamics of the maize genome. The high-quality genome sequences of the flint pool complement the maize pangenome and provide an important tool to study maize improvement at a genome scale and to enhance modern hybrid breeding.

DOI: 10.1038/s41588-020-0671-9

Source: https://www.nature.com/articles/s41588-020-0671-9

Nature Genetics:《自然—遗传学》,创刊于1992年。隶属于施普林格·自然出版集团,最新IF:41.307
官方网址:https://www.nature.com/ng/
投稿链接:https://mts-ng.nature.com/cgi-bin/main.plex


本期文章:《自然—遗传学》:Online/在线发表

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