日本名古屋大学Motoyuki Ashikari课题组取得一项新进展。他们提出水稻茎秆生长过程中赤霉素反应的拮抗调控。该研究于2020年7月15日发表于国际学术期刊《自然》杂志上。
他们显示水稻中节间茎的伸长受赤霉素的“促进剂”和“减速剂”的拮抗作用。他们将基因命名为ACCELERATOR OF INTERNODE ELONGATION 1（ACE1），该基因编码功能未知的蛋白质，使分生区的细胞具有细胞分裂的能力，从而导致赤霉素存在节间延伸。相比之下，编码锌指转录因子的DECECERATOR 1（DEC1）的上调，抑制了节间延伸，而DEC1的下调则允许节间延伸。
他们还表明，禾本科家族中由ACE1和DEC1介导的节间延伸机制是保守的。此外，对遗传多样性的分析表明，从历史上讲，ACE1和DEC1的突变有助于选择水稻驯化种群中较矮的植株，以增加其抗倒伏性，而野生稻种中较高的植株则可以适应深层水里的生长。他们对这些拮抗调节因子的鉴定，增强了他们对赤霉素反应的理解，这是除生物合成和赤霉素信号转导之外的另一种调节节间延伸和环境适应性的机制。
据了解，植株的大小在很大程度上取决于茎的生长。赤霉素刺激茎伸长。
附：英文原文
Title: Antagonistic regulation of the gibberellic acid response during stem growth in rice
Author: Keisuke Nagai, Yoshinao Mori, Shin Ishikawa, Tomoyuki Furuta, Rico Gamuyao, Yoko Niimi, Tokunori Hobo, Moyuri Fukuda, Mikiko Kojima, Yumiko Takebayashi, Atsushi Fukushima, Yasuyo Himuro, Masatomo Kobayashi, Wataru Ackley, Hiroshi Hisano, Kazuhiro Sato, Aya Yoshida, Jianzhong Wu, Hitoshi Sakakibara, Yutaka Sato, Hiroyuki Tsuji, Takashi Akagi, Motoyuki Ashikari
Issue&Volume: 2020-07-15
Abstract: The size of plants is largely determined by growth of the stem. Stem elongation is stimulated by gibberellic acid1,2,3. Here we show that internode stem elongation in rice is regulated antagonistically by an ‘accelerator’ and a ‘decelerator’ in concert with gibberellic acid. Expression of a gene we name ACCELERATOR OF INTERNODE ELONGATION 1 (ACE1), which encodes a protein of unknown function, confers cells of the intercalary meristematic region with the competence for cell division, leading to internode elongation in the presence of gibberellic acid. By contrast, upregulation of DECELERATOR OF INTERNODE ELONGATION 1 (DEC1), which encodes a zinc-finger transcription factor, suppresses internode elongation, whereas downregulation of DEC1 allows internode elongation. We also show that the mechanism of internode elongation that is mediated by ACE1 and DEC1 is conserved in the Gramineae family. Furthermore, an analysis of genetic diversity suggests that mutations in ACE1 and DEC1 have historically contributed to the selection of shorter plants in domesticated populations of rice to increase their resistance to lodging, and of taller plants in wild species of rice for adaptation to growth in deep water. Our identification of these antagonistic regulatory factors enhances our understanding of the gibberellic acid response as an additional mechanism that regulates internode elongation and environmental fitness, beyond biosynthesis and gibberellic acid signal transduction.
DOI: 10.1038/s41586-020-2501-8
Source: https://www.nature.com/articles/s41586-020-2501-8
Nature：《自然》，创刊于1869年。隶属于施普林格·自然出版集团，最新IF：69.504
官方网址：http://www.nature.com/
投稿链接：http://www.nature.com/authors/submit_manuscript.html
本期文章：《自然》：Online/在线发表
