小柯机器人

美国西奈山伊坎医学院Florian Krammer团队开发了血清学分析来检测人类中新冠病毒的血清转换。相关论文于2020年5月11日在线发表在《自然—医学》杂志上。

Title: A serological assay to detect SARS-CoV-2 seroconversion in humans

Author: Fatima Amanat, Daniel Stadlbauer, Shirin Strohmeier, Thi H. O. Nguyen, Veronika Chromikova, Meagan McMahon, Kaijun Jiang, Guha Asthagiri Arunkumar, Denise Jurczyszak, Jose Polanco, Maria Bermudez-Gonzalez, Giulio Kleiner, Teresa Aydillo, Lisa Miorin, Daniel S. Fierer, Luz Amarilis Lugo, Erna Milunka Kojic, Jonathan Stoever, Sean T. H. Liu, Charlotte Cunningham-Rundles, Philip L. Felgner, Thomas Moran, Adolfo Garca-Sastre, Daniel Caplivski, Allen C. Cheng, Katherine Kedzierska, Olli Vapalahti, Jussi M. Hepojoki, Viviana Simon, Florian Krammer

Issue&Volume: 2020-05-12

Abstract: Here, we describe a serological enzyme-linked immunosorbent assay for the screening and identification of human SARS-CoV-2 seroconverters. This assay does not require the handling of infectious virus, can be adjusted to detect different antibody types in serum and plasma and is amenable to scaling. Serological assays are of critical importance to help define previous exposure to SARS-CoV-2 in populations, identify highly reactive human donors for convalescent plasma therapy and investigate correlates of protection.

DOI: 10.1038/s41591-020-0913-5

Source: https://www.nature.com/articles/s41591-020-0913-5

Nature Medicine：《自然—医学》，创刊于1995年。隶属于施普林格·自然出版集团，最新IF：87.241
官方网址：https://www.nature.com/nm/
投稿链接：https://mts-nmed.nature.com/cgi-bin/main.plex