The germ-cell lineage ensures the continuity of life through the generation of male and female gametes, which unite to form a totipotent zygote.Wehave previously demonstrated that, by using cytokines, embryonic stem cells and induced pluripotent stem cells can be induced into epiblast-like cells ( ...
某次会议上我问过某大牛类似的问题， 我本以为会是***先把这个文章发出来。科研竞争惨烈，旁观者enjoy成果吧 ~ Tumor suppressor gene Rb is required for self-renewal of spermatogonial stem cells in mice. Hu YC , de Rooij DG , Page DC . Source Whitehead Institute, ...
Androgen deprivation therapy (ADT) is widely used in the treatment of metastatic, recurrent and locally advanced prostate cancer. However, ADT, which leads to castrate testosterone level, is associated with numerous side effects, such as sexual dysfunction, osteoporosis, obesity and cardiovascu ...
ATR acts stage specifically to regulate multiple aspects of mammalian meiotic silencing Hélène Royo, Haydn Prosser, Yaroslava Ruzankina, et al Genes Dev. 2013 27: 1484-1494 Access the most recent version at doi:10.1101/gad.219477.113 Abstract In mammals, homologs that fail to ...
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