博文
- 2021-02-21=drug=repurposing
- Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies These authors jointly supervised this work: Jan Baumbach, Josch Konstantin Pauling. LipiTUM, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Munic ...
- 2021-01-19=fetal development
- Metabolic Dynamics and Prediction of Gestational Age and Time to Delivery in Pregnant Women Highlights •Weekly metabolome of maternal blood changes dynamically through healthy pregnancy •A metabolic clock of five blood metabolites accurately predicts gestationa ...
- 2020-12-17-tumor=immunity
- 2020-12-17-tumor=immunity Anti-tumour immunity induces aberrant peptide presentation in melanoma Abstract Extensive tumour inflammation, which is reflected by high levels of infiltrating T cells and interferon-γ (IFNγ) signalling, improves the response of patients with melanom ...
- 2020-12-12=Condon Usage
- Translational efficiency across healthy and tumor tissues is proliferation‐related Abstract Different tissues express genes with particular codon usage and anticodon tRNA repertoires. However, the codon–anticodon co‐adaptation in humans is not completely un ...
- 2020-11-30=codon=usage=GB=2019
- Codon usage optimization in pluripotent embryonic stem cells Genome Biology volume 20 , Article number: 119 (2019) Abstract Background The uneven use of synonymous ...
- 2020-11-24=codon-usage
- Tissue-specific codon usage and the expression of human genes PNAS August 24, 2004 101 (34) 12588-12591; Abstract A diverse array of mechanisms regulate tissue-specific protein levels. Most research, however, has focused on the role of transcriptional regulation. Her ...
- 2020-11-17=Small RNA=Bacteria
- The noncoding small RNA SsrA is released by Vibrio fischeri and modulates critical host responses Plos Biology. Published: November 3, 2020 Abstract The regulatory noncoding small RNAs (sRNAs) of bacteria are key elements influencing gene expression; however, there has ...
- 2020-11-12=Big Data=Plant Pathology
- Application of Statistical Tools for Data Analysis and Interpretation in Rice Plant Pathology The Plant Pathology Challenge 2020 data set to classify foliar disease of apples Examples of common and economically important fungal diseases in an apple orchard impactin ...
- 2020-11-09=Ebola=scRNASeq
- Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics Published:November 06, 2020 Cell Highlights Interferon response is suppressed in infected cells but activated in bystander cells EBOV represses antiviral genes and upregul ...
- 2020-10-22=cfDNA-eccDNA
- Identification and characterization of extrachromosomal circular DNA in maternal plasma PNAS January 21, 2020 Significance We observed the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. We found that the plasma eccDNA molecules were ...
