博文
磷酸化蛋白质组学研究进展
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Frontiers in Biology的主编Hongjun Song教授（约翰.霍普金斯大学）和副主编余晨光教授（肯塔基大学）以及编委很给力，近来不断约请、收到国外著名大学学者的论文。
https://wap.sciencenet.cn/blog-54097-623828.html
上一篇：cover story(Frontiers in Biology, 2012 issue 5)
下一篇：遭遇假冒期刊
昨天刚刚收到主编转来的美国圣母大学（University of Notre Dame）的化学与生物化学系教授Amanda B. Hummon的一篇综述。题目为：Mass spectrometry-based phosphoproteomics in cancer research[full text]。这篇文章主要介绍了基于质谱技术的磷酸化蛋白质组学取得的进展，包括磷酸肽的鉴定、定量分析方法等。同时概括、讨论了目前利用磷酸化蛋白质组学技术在癌症研究中的一些新发现。
文章分为以下几个部分：
1 Introduction
2 Phosphoproteomic approaches for identification of phosphoproteins
2.1 Challenges of phosphoproteomics)
2.2 Separation and enrichment methods
2.3 LC-MS methods for phosphoproteomics
3 Phosphoproteomic approaches for quantification of phosphoproteins
4 Data interpretion
4.1 From spectra to peptide sequences
4.2 Quality control assessment
4.3 Phosphosite assignment
4.4 Quantification software
5 Phosphoproteomic approaches in cancer research
5.1 Phosphoproteomic research on DNA damage
5.2 Phosphoproteomic research on metastasis
5.3 Phosphoproteomic research for the discovery of biomarkers and targets for cancer diagnosis and new anti-cancer therapies
5.4 Phosphoproteomic research to explore kinase/phosphatase network and signaling pathways in cancer models
https://wap.sciencenet.cn/blog-54097-623828.html
上一篇：cover story(Frontiers in Biology, 2012 issue 5)
下一篇：遭遇假冒期刊
