Ten simple rules towards healthier research labs 让实验室运行更加健康与快乐的十条准则 作者：Fernando T. Maestre, 2019 Maestre教授认为， 在竞争激烈的学术环境中， 快乐、善良和谦逊的力量被低估了，他坚信它们是一种有利于科学实践的变革力量 。 Maestre认为，科研工作和生活可以更好地平衡，这些原则 ...
2022年1月12日，瑞士洛桑联邦理工学院的 Douglas Hanahan 教授在《Cancer Discovery》杂志上发表了癌症研究领域的年度重磅综述论文： Hallmarks of Cancer: New Dimensions 。该综述论文将已建立的癌症标志进一步拓展到了十四种，这些癌症标志的新维度有望促进研究人员更充分地了解癌症发展和恶性进展的机 ...
Structure-Based Discovery of N-Sulfonylpiperidine-3-carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication Abstract As a key element during HBV replication, a nucleocapsid is considered a promising target for the treatment of chronic hepatitis B. The prese ...
Increased immune escape of the new SARS-CoV-2 varia nt of concern Omicron Jie Hu # , Pai Peng # , Xiaoxia Cao # , Kang Wu, Quan-xin Long, Juan Chen, Kai Wang, Ni Tang and Ai-long Huang* A new detected SARS-CoV-2 variant Omicron (B.1.1.529) had reported from more than 80 ...
Title: Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro Published in Emerging Microbes Infections on January 06, 2022 Abstract: Coronavirus disease 2019 (COVID-19) caused by the emerging seve ...
The novel B.1.1.529 SARS-CoV-2 variant was designated Omicron (奥秘克戎) on the 26th November 2021, following its increasing prevalence in South Africa. Harbouring more than 30 mutations in its Spike protein, the principal concerns surround Omicron’s infectivity, virulence and ability to circumv ...
题目Title: Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera 共同第一作者Co-first author: Jie Hu (胡杰)、Xiao-yu Wei（魏晓宇）、Jin Xiang（向进） 摘要Abstract: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory sy ...
《 Frontiers in Cellular and Infection Microbiology 》 本期特刊 Metabolic Rewiring and Viral Infection 专题 简介 About this Research Topic Viruses are intracellular pathogens that rely on hijacking host resources to complete their life cycle. Specifically, upon infect ...
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