Ten simple rules towards healthier research labs 让实验室运行更加健康与快乐的十条准则 作者:Fernando T. Maestre, 2019 Maestre教授认为, 在竞争激烈的学术环境中, 快乐、善良和谦逊的力量被低估了,他坚信它们是一种有利于科学实践的变革力量 。 Maestre认为,科研工作和生活可以更好地平衡,这些原则 ...
Gluconeogenesis: Adding a new piece to the puzzle of malaria parasitism 碳水化合物代谢紊乱,包括低血糖和乳酸酸中毒,是疟疾的常见特征。 低血糖 是恶性疟原虫感染造成死亡的独立危险因素,其产生机制被认为是由疾病引起的厌食症、肝葡萄糖生成(hepatic glucose production)失调和疟原虫及免疫 ...
A new approach for submissions 为论文寻找合适的期刊可不是一件容易的事,也会影响文章发表的速度。为了帮助您快速、轻松地找到合适的期刊,Cell 出版社推出“集体审稿”(Community Review)制度,您可以同时选择多本Cell Press旗下期刊对您的文章进行评议 (终于可以“一稿多投”了,哈哈!) 。集体审稿制度 ...
我们时刻需要做出一些决定,这不是一件简单的事。头脑聪明的人眼观六路、耳听八方,综合各种感官接收到的外界信息,具体情况具体分析,最终做出合适的决策。科学家们把大脑的这种本领称为多感官或多模态感知。 “Who/what makes decisions in the cell?” How are decisions made in a cell ? The enigm ...
Review Article: PCK1 dysregulation in cancer: Metabolic reprogramming, oncogenic activation, and therapeutic opportunities Author : Jin Xiang ( 向进), Kai Wang, Ni Tang Abstract 摘要: The last few decades have witnessed an advancement in our understanding of mul ...
2022年1月12日,瑞士洛桑联邦理工学院的 Douglas Hanahan 教授在《Cancer Discovery》杂志上发表了癌症研究领域的年度重磅综述论文: Hallmarks of Cancer: New Dimensions 。该综述论文将已建立的癌症标志进一步拓展到了十四种,这些癌症标志的新维度有望促进研究人员更充分地了解癌症发展和恶性进展的机 ...
Structure-Based Discovery of N-Sulfonylpiperidine-3-carboxamides as Novel Capsid Assembly Modulators for Potent Inhibition of HBV Replication Abstract As a key element during HBV replication, a nucleocapsid is considered a promising target for the treatment of chronic hepatitis B. The prese ...
Increased immune escape of the new SARS-CoV-2 varia nt of concern Omicron Jie Hu # , Pai Peng # , Xiaoxia Cao # , Kang Wu, Quan-xin Long, Juan Chen, Kai Wang, Ni Tang and Ai-long Huang* A new detected SARS-CoV-2 variant Omicron (B.1.1.529) had reported from more than 80 ...