用传统方法在一个大型数据库中查询数百万个DNA序列，可能需要几个小时到数周，莱斯大学的计算机科学家发布兰博（RAMBO，repeated and merged bloom filter）程序，可快速对庞大的DNA数据库进行搜索，比现有方法快35倍。由于DNA测序非常流行，基因组数据集每两年就翻一番，快速搜索数据的工具非常重要。

RAMBO uses a data structure that has a significantly faster query time than state-of-the-art genome indexing methods as well as other advantages like ease of parallelization, a zero false-negative rate and a low false-positive rate.

RAMBO speeds searches on huge DNA databases

RAMBO speeds searches on huge DNA databases: Method cuts indexing times from weeks to hours, search times from hours to minutes -- ScienceDaily

1. Gaurav Gupta, Minghao Yan, Benjamin Coleman, Bryce Kille, R. A. Leo Elworth, Tharun Medini, Todd Treangen, Anshumali Shrivastava. Fast Processing and Querying of 170TB of Genomics Data via a Repeated And Merged BloOm Filter (RAMBO). SIGMOD/PODS '21: Proceedings of the 2021 International Conference on Management of Data, June 2021; DOI: http://dx.doi.org/10.1145/3448016.3457333