博文
- Crystal Structure of Human free fatty-acid receptor released
- High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875 Nature (2014) doi:10.1038/nature13494 Received 03 October 2013, Accepted 19 May 2014, Published online 20 July 2014 full text Abstract Human GPR40 receptor (hGPR40), also k ...
- Another class C GPCR structure released
- Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant Nature (2014) doi:10.1038/nature13396 Received20 January 2014 Accepted22 April 2014 Published online06 July 2014 ...
- install NVIDIA Optimus for laptop
- Nowadays, it is quite common and popular to have two dedicated graphic cards in laptop: usually, one is intergrated (eg: intel HD4xxx ) and the other is indepedent (eg: Nvidia GTX xxx). Such strategy can save laptop energy if we use integrated card for document task; while we can switch to inde ...
- convert multimedia between different formats
- Converting multimedia between different formats can be needed for different purposes. Although there are many tools under Windows, it is still feasible for such task under Linux OS including both command line and GUI end tool. Here are some popular methods for such purposes: ...
- Hazards Of Functional Groups
- Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. Most of the time in drug discovery are spend in optimizing compound properties including absorption, distribution, metabolism, and excretion (ADME). The four criteria all influence ...
- Class C GPCR structure released
- Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator Science DOI: 10.1126/science.1249489 Abstract he excitatory neurotransmitter glutamate induces modulatory actions via the metabotropic glutamate receptors (mGlus), which &n ...
- PyMOL v1.7.0.0 Release Notes
- Release Date: January 14, 2014. Graphics new labels visual additions : connectors, backgrounds, and outlines Note: We are building an interface that will make it easier to control labels interactively so that you won’t need to remember all of these settings explicitly, but th ...
- FDA Approves 27 New Drugs in 2013
- The new drug approvals for 2013 were mostly cancer drugs and drugs for orphan diseases. Other therapeutic areas included metabolic and endocrinological therapies (two type 2 diabetes drugs and one dyslipidaemia drug), antivirals (two hepatitis C virus (HCV) drugs and an HIV drug) and medical ima ...
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