Trends in pharmacological science, Volume 36, Issue 1, p22–31, January 2015 Abstract Generic residue numbers facilitate comparisons of, for example, mutational effects, ligand interactions, and structural motifs. The numbering scheme by Ballesteros and Weinstein for residues within the cl ...
Nature (2014) doi:10.1038/nature14063 Received 12 September 2014 Accepted 12 November 2014 Published online 15 December 2014 full text: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14063.html The ryanodine receptors ...
From http://www.gizmag.com By Anthony Wood Researchers from the Harvard Stem Cell Institute (HSCI) have shown that injections of a protein dubbed GDF11, when administered to older mice, appear to cause a reversal of many signs of aging. Analysis showed that every major organ ...
The Nobel Prize in Chemistry 2014 was awarded jointly to Eric Betzig, Stefan W. Hell and William E. Moerner for the development of super-resolved fluorescence microscopy . From http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2014/
Activation of G-protein-coupled receptors correlates with the formation of a continuous internal water pathway. Shuguang Yuan, Slawomir Filipek, Krzysztof Palczewski, Horst Vogel Nature Communication doi:10.1038/ncomms5733 full text news story A schemat ...
Most proteins undergo post translation in vivo including phosphorylation, acetylation, methylation, palmitoylation and so on. Those modified property sometimes contribute great importance on protein stability and physiological functions. However, currently, parameterizing modified covalen ...
High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875 Nature (2014) doi:10.1038/nature13494 Received 03 October 2013, Accepted 19 May 2014, Published online 20 July 2014 full text Abstract Human GPR40 receptor (hGPR40), also k ...
Structure of the human class C GPCR metabotropic glutamate receptor 5 transmembrane domain in complex with the negative allosteric modulator mavoglurant Nature (2014) doi:10.1038/nature13396 Received20 January 2014 Accepted22 April 2014 Published online06 July 2014 ...
博文
视频
基金
相册
收藏
积分
会议