从中国疯狗分离的一个狂犬病毒街毒株的全基因组测序

Complete Genome Sequence of a Street Rabies Virus Isolated from a Rabid Dog in China 

2008年从中国安徽省的一只狗分离到一株狂犬病街毒(RABV)，命名为DRV-AH08。对其全基因组进行了测序，发现它与近期在中国及其他亚洲国家分离的RABV密切相关，同源性为87%-98%；但它与RABV分支1 (clade I )中的“全球广布(cosmopolitan)”组的病毒关系较远，同源性仅为84%至85%。

A rabies virus (RABV) was isolated from a dog in Anhui Province, China, in 2008. The virus was designated DRV-AH08. Its entire genome was sequenced and found to be closely related to RABV recently isolated in China and other Asian countries (homology of 87 to 98%) but distantly related to RABV in the “cosmopolitan” group (homology of 84 to 85%) in the clade I of RABV.

作者：

Fulai Yu,^a   Guoqing Zhang,a,^b    Shaobo Xiao,^a    Liurong Fang, ^a     Gelin Xu, ^c

  Jiaxing Yan, ^c    Huanchun Chen,^a   and    Zhen F. Fu^a,^b

作者单位：

a)      State-Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China 

b)      Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA 

c)      Wuhan Institute of Biological Products, Sino Pharma, Wuhan, China 

 

原载： J. Virology.  2012, 86(19):10890. DOI: 10.1128/JVI.01775-12. 

原文下载：J. Virol.-2012-Yu-10890-1.pdf

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