HOXA9追踪揭示RBM5的双重功能和治疗急性髓性白血病的潜力

https://www.ebiotrade.com/newsf/2024-1/20240113045935682.htm

http://www.pubmedplus.cn/P/SearchQuickResult?wd=13ec59ca-76a1-4434-9277-8e2e8d6a31e2

1. RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9.

Mengli Zhang,Judith Hyle,Xiaowen Chen,Ye Xin,Yingcai Jin,Jianxiang Zhang,Xue Yang,Xinfeng Chen,Shaela Wright,Zhenling Liu,Wojciech Rosikiewicz,Beisi Xu,Liusheng He,Hong Liu,Nana Ping,Depei Wu,Feiqiu Wen,Chunliang Li,Peng Xu

Cyrus Tang Medical Institute, National Clinical Research Center for Hematologic Diseases, State Key Laboratory of Radiation Medicine and Protection, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, 215123, Jiangsu, China.

Genome Biol (P 1474-760X E 1474-7596) 2024 年 25 卷 1 期 16 页

PMID：38216972 相似文献

文摘 DOI链接 BioMed CentralPubMed CentralEurope PubMed Central

https://pubmed.ncbi.nlm.nih.gov/38216972/

MeSH terms

• Cell Cycle Proteins / metabolism

• Cell Proliferation

• DNA-Binding Proteins / metabolism

• Homeodomain Proteins* / genetics

• Homeodomain Proteins* / metabolism

• Humans

• Leukemia, Myeloid, Acute* / genetics

• Leukemia, Myeloid, Acute* / metabolism

• Neoplasm Proteins / metabolism

• Oncogene Proteins / metabolism

• RNA-Binding Proteins / genetics

• Tumor Suppressor Proteins / metabolism

http://www.pubmedplus.cn/P/SearchQuickResult?wd=092f0c40-80ef-4a73-96d9-237d89d55b96

• 主题词

• 记录数占%

01.	Humans	79 篇	78.218%
02.	Animals	63 篇	62.376%
03.	Homeodomain Proteins	63 篇	62.376%
04.	Mice	52 篇	51.485%
05.	Leukemia, Myeloid, Acute	47 篇	46.535%
06.	DNA-Binding Proteins	42 篇	41.584%
07.	Neoplasm Proteins	33 篇	32.673%
08.	Tumor Suppressor Proteins	33 篇	32.673%
09.	Myeloid Ecotropic Viral Integration Site 1 Protein	31 篇	30.693%
10.	RNA-Binding Proteins	31 篇	30.693%

https://kns.cnki.net/kns8s/search?classid=WD0FTY92&kw=RBM5&korder=SU

•  非小细胞肺癌 (8)

•  RBM6-RBM5 (7)

•  RBM10 (7)

•  肺腺癌 (7)

•  临床意义 (5)

•  肿瘤抑制基因 (5)

•  RNA (4)

•  前列腺癌 (4)

•  lncRNA RBM5-AS1 (3)

•  RBM (3)

•  小细胞肺癌 (3)

•  可变剪切 (3)

•  细胞凋亡 (3)

•  肺癌细胞 (3)

•  catenin (2)

•  化疗耐药 (2)

•  肺腺癌细胞 (2)

•  子宫内膜癌 (2)

•  乳腺癌 (2)

•  细胞增殖 (2)

https://fx.wanfangdata.com.cn/keytrends/detail?theme_name=RBM5

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