||
黑色素瘤中PTEN蛋白的肿瘤抑制活性
https://www.ebiotrade.com/newsf/2024-1/20240110034647833.htm
AKT活性能够克服PTEN的抗肿瘤活性,促进黑色素瘤的生长和侵袭,这表明PTEN对AKT的调节在黑色素瘤形成的后期,如转移,尤为重要。研究人员还确定,AKT通过蛋白质翻译的mTOR调节因子控制FRA1蛋白的产生,从而促进黑色素瘤的进展。
http://www.pubmedplus.cn/P/SearchQuickResult?wd=e399c259-be1b-43d8-9571-3cd866368afc
01. | Cell Line, Tumor | 211 篇 | 100.000% |
02. | Gene Expression Regulation, Neoplastic | 211 篇 | 100.000% |
03. | PTEN Phosphohydrolase | 211 篇 | 100.000% |
04. | Phosphatidylinositol 3-Kinases | 211 篇 | 100.000% |
05. | Humans | 205 篇 | 97.156% |
06. | Signal Transduction | 161 篇 | 76.303% |
07. | Proto-Oncogene Proteins c-akt | 150 篇 | 71.090% |
08. | Cell Proliferation | 109 篇 | 51.659% |
09. | MicroRNAs | 80 篇 | 37.915% |
10. | Female | 75 篇 | 35.545% |
https://kns.cnki.net/kns8s/search?classid=WD0FTY92&kw=PTEN&korder=SU
(788)
(585)
(568)
(443)
(421)
(384)
(350)
(305)
(288)
(253)
(248)
(232)
(224)
(216)
(208)
(191)
(182)
(176)
(170)
(162)
https://fx.wanfangdata.com.cn/keytrends/detail?theme_name=PTEN
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-5-17 07:07
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社