SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells Abstract Glomerular matrix accumulation is a hallmark of diabetic nephropathy. Recent studies showed that overexpression of the transcription factor SREBP-1 induces glomerulosclerosis. TGFβ1 is a key profi ...
Hot spots of DNA double-strand breaks and genomic contacts of human rDNA units are involved in epigenetic regulation J Mol Cell Biol mju038 first published online October 3, 2014 doi: 10.1093/jmcb/mju038 Abstract DNA double-strand breaks (DSBs) ...
2014年6月11日,国际学术期刊 Journal of Molecular Cell Biology 在线发表了中国科学院上海生物化学与细胞生物学研究所葛高翔研究组的最新研究成果 “ Snail and Slug mediate tamoxifen resistance in breast cancer cells through activation of EGFR–ERK independent of epithelial–mesenchymal transition ”。该 ...