MBRidge: an accurate and cost-effective method for profiling DNA methylome at single-base resolution Abstract Organisms and cells, in response to environmental influences or during development, undergo considerable changes in DNA methylation on a genome-wide scale, which are linked to a ...
近日,国际学术期刊 Journal of Molecular Cell Biology 在线发表了来自中国科学院生物物理所、美国 UCLA 、昆明医科大学和青岛生物能源与过程所合作完成的最新研究成果:“ New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16 ”,该研究阐述了天然免疫信号传导重要蛋 ...
2015年1月13日,国际学术期刊 Journal of Molecular Cell Biology 在线发表了中国科学院上海生命科学研究院生物化学与细胞生物学研究所陈德桂研究组的最新研究成果 “ JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice ”,揭示了软 ...