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国内权威的信息检索平台与国外的同类信息平台相比,重要信息资源的导航和关联远远不够,相关信息搜索和检索分析功能比较差,信息检索效率较低,没有发挥网络数据库的重要作用和威力。
同方的中国知网和万方数据库大家用的很多,比较熟悉。我们看看美国的PUBMED医学信息平台的资源关联和检索功能,非常强大。
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Despite being a critical survivorship care issue, there is a clear gap in current knowledge of the optimal treatment of sexual dysfunction in men with prostate cancer. There is sound theoretical rationale and emerging evidence that exercise may be an innovative therapy to counteract sexual dysfunction in men with prostate cancer. Furthermore, despite the multidimensional aetiology of sexual dysfunction, there is a paucity of research investigating the efficacy of integrated treatment models. Therefore, the purpose of this study is to: 1) examine the efficacy of exercise as a therapy to aid in the management of sexual dysfunction in men with prostate cancer; 2) determine if combining exercise and brief psychosexual intervention results in more pronounced improvements in sexual health; and 3) assess if any benefit of exercise and psychosexual intervention on sexual dysfunction is sustained long term.
METHODS/DESIGN:A three-arm, multi-site randomised controlled trial involving 240 prostate cancer survivors will be implemented. Participants will be randomised to: 1) 'Exercise' intervention; 2) 'Exercise + Psychosexual' intervention; or 3) 'Usual Care'. The Exercise group will receive a 6-month, group based, supervised resistance and aerobic exercise intervention. The Exercise + Psychosexual group will receive the same exercise intervention plus a brief psychosexual self-management intervention that addresses psychological and sexual well-being. The Usual Care group will maintain standard care for 6 months. Measurements for primary and secondary endpoints will take place at baseline, 6 months (post-intervention) and 1 year follow-up. The primary endpoint is sexual health and secondary endpoints include key factors associated with sexual health in men with prostate cancer.
DISCUSSION:Sexual dysfunction is one of the most prevalent and distressing consequences of prostate cancer. Despite this, very little is known about the management of sexual dysfunction and current health care services do not adequately meet sexual health needs of survivors. This project will examine the potential role of exercise in the management of sexual dysfunction and evaluate a potential best-practice management approach by integrating pharmacological, physiological and psychological treatment modalities to address the complex and multifaceted aetiology of sexual dysfunction following cancer.
TRIAL REGISTRATION:Australian New Zealand Clinical Trials Registry ACTRN12613001179729.
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Living with prostate cancer: randomised controlled trial of a multimodal supportive care intervention for men with prostate cancer.[BMC Cancer. 2011]
Review Exercise therapy for sexual dysfunction after prostate cancer.[Nat Rev Urol. 2013]
Review Psychosocial interventions for men with prostate cancer.[Cochrane Database Syst Rev. 2013]
Improving sexual health in men with prostate cancer: randomised controlled trial...
Improving sexual health in men with prostate cancer: randomised controlled trial...
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http://www.ncbi.nlm.nih.gov/pubmed/24641777?dopt=Abstract
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