Breast Cancer Res.：有益胆固醇或增加乳腺癌发病风险

高密度脂蛋白（high density lipoprotein，HDL）被认为是一种"有益胆固醇"，高水平的HDL能够预防心脏病产生。然而常言道"甲之熊掌，乙之砒霜"，动物实验表明高水平的HDL也会增加乳腺癌发病风险，增加癌症恶性程度。

托马斯杰斐逊大学生化和分子生物学系Philippe Frank博士领导的研究人员发现乳腺癌细胞表明的HDL受体对乳腺癌发病有重要作用，该分子或为治疗乳腺癌的新靶点。相关报道发表在近期的Breast Cancer Research杂志上。

为了研究HDL在分子水平对癌细胞的影响，Frank博士领导的科学家在培养的乳腺癌细胞系中加入HDL，观察癌细胞的变化发现癌细胞开始转移。

http://www.bioon.com/tm/others/584898.shtml 

检索策略  high density lipoprotein and  Breast Cancer

信息平台  http://www.pubmedplus.cn/Pubmed/Statistic

分析结果

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi?refresh=T&ID=28992

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