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One fascinating set of experiments that relates to the concept of establishing or promoting a reflex pathway for micturition is that reported by Xiao and de Groat (1999) . These individuals created a skin to central nervous system to bladder reflex pathway in cats by intradural microanastomosis of the left L7 ventral root to the S1 ventral root, leaving the L7 dorsal root intact to conduct cutaneous afferent signals. A detrusor contraction was able to be initiated by scratching the skin or by percutaneous electrical stimulation in the L7 dermatome. This new reflex pathway could initiate voiding without striated sphincter dyssynergia. This reflex could be elicited after transecting the spinal cord at the L2-L3 or L7-S1 levels. The pathway is mediated by cholinergic transmission at both ganglionic and peripheral levels, as shown by cholinergic blockade experiments. Thus, in this experimental model, somatic motor axons can innervate parasympathetic bladder ganglion cells and thus transfer somatic reflex activity to the lower urinary tract.
我认为,不可因为肖最近的事而否认这篇文章的价值; 同时亦要还原"肖氏反射弧"的本来面目。
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