研究进展：

http://www.bioon.com/biology/neuroscience/449473.shtml

Neurology：睡眠失调可能是帕金森氏症的前兆

知识发现平台：

 http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

Start A-Literature C-Literature B-list Filter Literature

A-query: Parkinson disease C-query: sleep behavior disorder The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 815 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 26490 and can be accessed from the start page after you leave this session. There are 907 terms on the current B-list (242 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

job id # 26490 started Fri Jul 30 03:09:39 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
26490 Search ARROWSMITH A
A_query_raw: Parkinson disease Fri Jul 30 03:10:17 2010

A query = Parkinson disease started Fri Jul 30 03:10:18 2010
A query resulted in 42621 titles
26490 Search ARROWSMITH C
C_query_raw: sleep behavior disorder Fri Jul 30 03:10:30 2010

C: sleep behavior disorder 36854

A: pubmed_query_A 42621

AC: ( Parkinson disease ) AND ( sleep behavior disorder ) 815

C query = sleep behavior disorder started Fri Jul 30 03:10:31 2010
C query resulted in 36854 titles
A AND C query resulted in 815 titles
24408 B-terms ready on Fri Jul 30 03:17:02 2010

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
907 B-terms left after filter executed Fri Jul 30 03:42:18 2010

B-list on Fri Jul 30 03:45:51 2010
1 hypocretin
2 serotonin transporter gene
3 transporter gene
4 fdg
5 orexin a
6 epsilon allele
7 cyp2d6
8 epsilon4 allele
9 erp
10 5-ht1a
11 bdnf
12 cannabinoid receptor
13 single nucleotide polymorphism
14 p300
15 ssri
16 cox-2
17 cyp2c19
18 meg
19 alcohol withdrawal
20 a2a
21 microrna
22 apoe
23 genome wide
24 dsm
25 dlb
26 cit
27 monoamine oxidase b
28 5-ht2c
29 apolipoprotein e
30 adenosine a2a receptor
31 dopamine d2 receptor
32 rem
33 essential tremor
34 cb1
35 promoter polymorphism
36 dopamine receptor
37 comt
38 candidate gene
39 vglut1
40 spinocerebellar ataxia
41 d3 receptor
42 ghrelin
43 glutamate receptor
44 polymorphism promoter
45 parkin
46 5-ht2a
47 repetitive behavior
48 5-ht2
49 casein kinase
50 prion protein gene
51 vglut2
52 mao
53 fraxe
54 metabolic syndrome
55 cpap
56 prion protein
57 ect
58 prnp
59 neurotrophic factor gene
60 sca6
61 monoamine oxidase a
62 trna leu uur
63 polymorphism promoter region
64 shy
65 leptin
66 snp
67 body mass index
68 immediate early gene
69 apoe epsilon allele
70 cag
71 glycogen synthase kinase
72 statin
73 dj-1
74 sirtuin
75 chaperone
76 creb
77 ubiquitin
78 catechol o-methyltransferase
79 abeta
80 gene promoter
81 phox2b
82 crh
83 gsk-3beta
84 signal regulated kinase
85 gaba a receptor
86 monoamine oxidase
87 microsatellite
88 glycogen synthase
89 tyrosine hydroxylase
90 tic
91 wnt
92 icf
93 circling
94 han
95 opiate receptor
96 gabaa
97 hib
98 thip
99 opioid receptor
100 c fos
101 mmpi
102 5-ht3
103 girk2
104 pituitary hormone
105 sca3
106 brain gene
107 pten
108 mri
109 calbindin
110 spike
111 cramp
112 gene variant
113 pet
114 nf kappab
115 adl
116 dopa
117 corticotropin releasing hormone
118 kv3
119 protein gene codon
120 epilepsy
121 rls
122 gene schizophrenia
123 mutation codon
124 galanin
125 14q
126 ngfi
127 major affective disorder
128 gad
129 gaba a
130 clock
131 ventricular size
132 apolipoprotein epsilon allele
133 il-6
134 cystatin c
135 bax
136 tms
137 diazepam binding inhibitor
138 adenosine a1 receptor
139 transporter
140 fp
141 il-2
142 gaba
143 bone mineral density
144 neurotensin
145 hydrocephalus
146 meningioma
147 proopiomelanocortin gene
148 tremor
149 promoter region
150 huntington disease
151 shr
152 hyperparathyroidism
153 triplet repeat
154 dopamine beta hydroxylase
155 circadian rhythm
156 scn8a
157 adas
158 cdna
159 trh
160 neurotensin receptor
161 fk506
162 d1
163 rest
164 cbt
165 junb
166 cue
167 cytochrome p-450
168 gene associated
169 adiposity
170 erk
171 adeno
172 laterality
173 msa
174 pars
175 olfactory
176 locomotor activity
177 alzheimer disease
178 igf i
179 anxiety
180 cystatin
181 p-450
182 lh
183 dream
184 n acetyltransferase
185 amyotrophic lateral sclerosis
186 chi
187 noun
188 small conductance
189 tau
190 nadph oxidase
191 5'-untranslated region
192 enhancer
193 cytokine production
194 dbs
195 igf-1
196 tsh
197 spatial learning
198 d2
199 il-10
200 maoa
201 ro
202 codon
203 parvalbumin
204 mrs
205 polymorphism 3'-untranslated region
206 alpha gene
207 paget disease bone
208 protein kinase c
209 strabismus
210 twin
211 retinitis pigmentosa
212 dystonia
213 bcl-2
214 lobe
215 spino
216 lethargic
217 bright
218 lip
219 pomc
220 neuropeptide y
221 decarboxylase
222 chemokine
223 intronic
224 shh
225 click
226 hmg coa reductase
227 oscillator
228 anorexia
229 gene not
230 crf
231 endothelin
232 thyrotropin releasing hormone
233 tachykinin
234 nr2a
235 huntington
236 sigma
237 mt1
238 fos
239 obesity
240 brain protein
241 calcium channel
242 tnf alpha

Start A-Literature C-Literature B-list Filter Literature

AB literature   B-term   BC literature   Parkinson disease fdg sleep behavior disorder 1: Functional brain imaging in pure akinesia with gait freezing: [18F] FDG PET and [18F] FP-CIT PET analyses. 2009 Add to clipboard 2: Frontal FDG-PET activity correlates with cognitive outcome after STN-DBS in Parkinson disease. 2009 Add to clipboard 3: Assessing the microlesion effect of subthalamic deep brain stimulation surgery with FDG PET. 2009 Add to clipboard 4: Cortical hypometabolism assessed by a metabolic ratio in Parkinson's disease primarily reflects cognitive deterioration-[18F]FDG-PET. 2009 Add to clipboard 5: STN-DBS activates the target area in Parkinson disease: an FDG-PET study. 2008 Add to clipboard 6: Diagnostic value of brain MRI and 18F-FDG PET in the differentiation of Parkinsonian-type multiple system atrophy from Parkinson's disease. 2008 Add to clipboard

 

 

 

 

 

 

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