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Levoleucovorin (Calcium) | 左亚叶酸钙
MCE 国际站:Levoleucovorin (Calcium)
中文名:左亚叶酸钙
CAS:80433-71-2
品牌:MedChemExpress (MCE)
存储条件:4°C, sealed storage, away from moisture and light
生物活性:Levoleucovorin Calcium (Calcium levofolinate),Leucovorin Calcium (HY-13664) 的左旋亚型,具有抗肿瘤作用. Levoleucovorin Calcium 也是5-fluorouracil (HY-90006) 抗癌细胞毒性的增强剂 [1][2]。
体内:左旋叶酸钙(6、20 或 60 mg/kg/天;静脉注射;持续 4 周)增强 5 的毒性-氟尿嘧啶[2]。
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作用靶点:Antifolate
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参考文献:[1]. National Center for Biotechnology Information. PubChem Compound Summary for CID 135500522, Levoleucovorin calcium.
[2]. Murakami Y, et al. Effects of levofolinate calcium on subacute intravenous toxicity of 5-fluorouracil in rats. J Toxicol Sci. 1998 May;23 Suppl 1:11-29.
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