GIP, human (TFA)

国际站：GIP, human (TFA)

中文名：抑胃肽三氟乙酸盐 (人)

品牌：MedChemExpress (MCE)

存储条件：Protect from light, stored under nitrogen.Powder: -80°C, 2 years; -20°C, 1 year.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：GIP，人 TFA，一种由 42 个氨基酸组成的肽激素，是葡萄糖依赖性胰岛素分泌的刺激剂和胃酸分泌的弱抑制剂。 GIP，人类 TFA 作为肠道 K 细胞响应营养摄入而释放的肠促胰岛素激素^[1][2][3]。 

体外：胃抑制性多肽 (GIP) 对脂肪组织和脂质代谢产生多种外周作用，从而导致餐后脂质沉积增加^[1]。 GIP，人类在脂质代谢和肥胖的发展中起着至关重要的作用。

参考文献：[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.[2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699.[3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review. Peptides. 2020;125:170224.