2-Hydroxy Atorvastatin-d5 (disodium)

国际站：2-Hydroxy Atorvastatin-d5 (disodium)

CAS：1276537-19-9

品牌：MedChemExpress (MCE)

存储条件：-20°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

生物活性：2-Hydroxy Atorvastatin-d5 (disodium) 是 2-Hydroxy Atorvastatin disodium 的氘代物。

体外：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献：[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.