Effect of Sr on the microstructure and biodegradable behavior of Mg–Zn–Ca-Mn alloys for implant application

• Jingfeng Wang^a, b, , , Yao Ma^a, Shengfeng Guo^c, , , Weiyan Jiang^a, Qingshan Liu^a

• ^a National Engineering Research Center for Magnesium Alloys, College of Materials Science and Engineering, Chongqing University, Chongqing 400044, PR China

• ^b State Key Laboratory of Mechanical Transmission, Chongqing University, Chongqing 400044, PR China

• ^c Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China

Abstract

In this paper, the effect of Sr on the microstructure and bio-corrosion behavior of Mg_65.2−xZn₃₀Ca₄Mn_0.8Sr_x (x = 0, 0.3, 0.5 and 0.8) amorphous matrix composite were investigated by X-ray diffraction, differential scanning calorimetry, scanning electron microscope, electrochemical measurements, immersion test and in vitro cytotoxicity test, respectively. Compared to the Mg–Zn–Ca-Mn alloy, the Sr-bearing alloys with minor Sr incorporation improved the glass formation ability and bio-corrosion resistance significantly. The corrosion products of the Mg_65.2−xZn₃₀Ca₄Mn_0.8Sr_x (x = 0, 0.3, 0.5 and 0.8) alloys mainly contained Zn(OH)₂, hydroxyapatite and phosphate after 124 h static immersion test, which were beneficial to the bone growth. The results suggested that the novel Mg_64.7Zn₃₀Ca₄Mn_0.8Sr_0.5 alloy possessed a good corrosion resistance and biocompatibility, showing a promising candidate for the biodegradable implants.

https://www.sciencedirect.com/science/article/pii/S026412751830340X