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最近《自然》和《自然•神经科学》同时发表了两篇关于VIP+抑制性神经元在神经回路中的作用。借此机会,回顾总结了一下近年来对三种主要的抑制性神经元的研究(如下)。总的来说,系统神经科学在研究重点从兴奋性神经元转向抑制性神经元、麻醉动物转向清醒动物、从in vitro转向in vivo.
Electrophysiology properties of PV+ and SOM+ inhibitory neurons in primary visual cortex in anesthetized mice (Liu et al., 2009; Kerlin et al., 2010; Ma et al., 2010; Runyan et al., 2010)
Effect of PV+, SOM+ inhibitory neurons on excitatory neurons in primary visual cortex in anesthetized or awake mice (Atallah et al., 2012; Lee et al., 2012; Wilson et al., 2012)
Electrophysiology properties of SOM+ inhibitory neuron and its effect on excitatory neuron in primary somatosensory cortex in awake behaving mice (Gentet et al., 2012)
Local circuits SOM+ inhibitory neuron and excitatory neuron in primary visual cortex in anesthetized and awake mice (Adesnik et al., 2012)
Effect of PV+, SOM+ inhibitory neurons on excitatory neurons in CA1 in behaving mice (Royer et al., 2012)
Local circuits among inhibitory neuron in layer 1 in acute rat sensorimotor cortex slice (Jiang et al., 2013)
SOM+ inhibitory neuron in primary somatosensory cortex in acute mouse slice (Xu et al., 2013)
Local circuits among PV+, SOM+ and VIP+ in acute mouse slice (Pfeffer et al., 2013)
Circuitry function of VIP+ inhibitory neuron in behaving mice (Lee et al., 2013; Pi et al., 2013)
Reference
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