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Neuron——脆性X综合征中过表达的mRNA可能起对抗疾病的作用
1. TRAP-Seq Identifies Differentially Translating mRNAs in Fmr1–/y CA1 Pyramidal Neurons
2. Differentially Translated mRNAs in Fmr1–/y CA1 Include FMRP Targets and mAChR Transcripts
3. M1 and M4 Are Excessively Synthesized and Overexpressed in Fmr1–/y CA1 Pyramidal Neurons
4. M4 Synthesis Downstream of mGlu5 Is Mimicked and Occluded in the Fmr1–/y Hippocampus
5. Enhancement of M4 Normalizes Excessive Protein Synthesis in the Fmr1–/y Hippocampus
6.M4 PAM Corrects Exaggerated mGluR-LTD in the Fmr1–/y Mouse
7. M4 PAM Corrects the Exaggerated AGS Phenotype in the Fmr1–/y Mouse
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