博文
Mini-Review：Role of BDNF in the taste system
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Mini-Review
Role of BDNF in the taste system
Lingbin Meng , Xiaolei Chen , Rongqiang Yang & Rui Ji
Abstract
Neurotrophins are a family of proteins that regulateneural survival, development, function and plasticity in the central and theperipheral nervous system. There are four neurotrophins: NGF, BDNF, NT-3 andNT-4. Among them, BDNF is mostly studied in the taste system due to its highexpression. Recent studies have shown BDNF play an important role in thedevelopmental and mature taste system, by regulating survival of taste cellsand geniculate ganglion neurons, and maintaining and guiding taste nerveinnervations. These studies imply BDNF has great potentialities for therapeuticusage to enhance sensory regeneration following nerve injury, with aging, andin some neurodegenerative diseases.
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上一篇：Frontiers in Biology 2014年 第6期
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