绝大多数是第一作者和通讯作者。其它刊物上论文包括Nature、JACS等。乃当前世界上全合成最厉害的有机化学家。

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K. C. Nicolaou

K.C.Nicolaou简介（共177篇）

 

 

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K.C.Nicolaou（1998）        K.C.Nicolaou（2009）

 

Cover Picture: Total Synthesis and Absolute Configuration of the Bisanthraquinone Antibiotic BE-43472B (Angew. Chem. Int. Ed. 19/2009)

K. C. Nicolaou, Prof. Dr. 1 2 *, Yee Hwee Lim 1 2, Jochen Becker, Dr. 1 2

1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA) 2Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 (USA), Fax: (+1) 858-784-2469

email: K. C. Nicolaou (kcn@scripps.edu)

^*Correspondence to K. C. Nicolaou, ¹Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA)

These authors contributed equally to this work.

Keywords

anthraquinones ?antibiotics ?cascade reactions ?Diels-Alder reactions ?total synthesis

Abstract

A cascade sequence featuring a Diels-Alder reaction, a lactolization, and an SN(Ar)-type substitution forms the core of the bisanthraquinone antibiotic BE-43472B in its first total synthesis, which K. C. Nicolaou et al. describe in their Communication on page 3444 ff. The background of the cover picture is a photograph of Ecteinascidia turbinata (courtesy of John Easley Photography), the marine source of the streptomyces strain producing this antibiotic.

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