2015新发表的文献：

DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain.

主要结论：

1. 通过DNA甲基化信息，可以用唾液采集来研究精神疾病；

2. 唾液DNA甲基化比血液variance更大

There was more variability in CpG sites from saliva than blood, which may reflect its heterogeneity.

3. 相对血液，唾液DNA甲基化更“象”脑部变化；

Finally, DNA methylation in saliva appeared more similar to patterns from each of the brain regions examined overall than methylation in blood.

http://www.ncbi.nlm.nih.gov/pubmed/25355443

 

转载本文请联系原作者获取授权，同时请注明本文来自熊江辉科学网博客。
链接地址：https://wap.sciencenet.cn/blog-508476-853832.html

上一篇：基于表观遗传学的纵向队列研究：奢侈但是大有可为？
下一篇：表观遗传流行病学队列研究的方法学：还很原始