基因编码蛋白,转座子编码调节元件。前者已经是常识了,而后者也有例子出现。参考文献:Transposable Elements Re-Wire and Fine-Tune the Transcriptome(Cowley M, Oakey RJ (2013) Transposable Elements Re-Wire and Fine- Tune the Transcriptome. PLoS Genet 9(1): e1003234. doi:10.1371/journal.pgen.1003234)。原文引用1“Indeed, TEs are major players in the production of small RNAs that regulate host gene transcripts. For example, TE-encoded piRNAs are required to establish a gradient of maternal Nanos mRNA transcripts in the early Drosophila embryo [50]”(50. Rouget C, Papin C, Boureux A, Meunier AC, Franco B, et al. (2010) Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo. Nature 467: 1128–1132.),原文引用2“Mammals also utilise TE-encoded small RNAs to regulate host gene expression. In mice, the imprinted gene Rasgrf1, like Mcts2, is under the control of differential DNA methylation on the two alleles. At this locus, DNA methylation is established in the paternal germline (Figure 3B), opposite to that for Mcts2, and this requires TE-encoded piRNAs [51].”(51. Watanabe T, Tomizawa S, Mitsuya K, Totoki Y, Yamamoto Y, et al. (2011) Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science 332: 848–852.)