Identification of a spontaneous frame shift mutation in a nonreference Arabidopsis thaliana accession using whole genome sequencing

Identification of a spontaneous frame shift mutation in a nonreference Arabidops.pdf

精细定位到530kb后直接用高通量测序的方法,确定侯选基因

 

精细定位前的做法:

High-throughput genotyping by whole-genome resequencing

High-throughput genotyping by whole-genome resequencing.pdf

Parent-independent genotyping for constructing an ultrahigh-density linkage map based on population sequencing

Parent-independent genotyping for constructing anultrahigh-density linkage map b.pdf

几篇文章合在一起,暗示了一种作图的新方法和方向

............................................

Theor Appl Genet. 2011 May;122(8):1467-80. Epub 2011 Feb 23.
Mapping with RAD (restriction-site associated DNA) markers to rapidly identify QTL for stem rust resistance in Lolium perenne.

这也是一种利用方法

....................

Genome sequencing reveals agronomically important loci in rice using MutMap

Genome sequencing reveals agronomically important.pdf

.....................

User guide for mapping-by-sequencing in Arabidopsis(http://yunpan.cn/QGuCWJgyP8rU8)

这篇文章的标题里直接用了mapping-by-sequencing.当然这篇文章是进行的理论模拟.有条件的可以按照文章提供的理论,用真实的实验数据来整整.

通过PubMed搜索了一下还有另外4篇文章:

1.
Barley whole exome capture: a tool for genomic research in the genus Hordeum and beyond.
Mascher M, Richmond TA, Gerhardt DJ, Himmelbach A, Clissold L, Sampath D, Ayling S, Steuernagel B, Pfeifer M, D'Ascenzo M, Akhunov ED, Hedley PE, Gonzales AM, Morrell PL, Kilian B, Blattner FR, Scholz U, Mayer KF, Flavell AJ, Muehlbauer GJ, Waugh R, Jeddeloh JA, Stein N.
Plant J. 2013 Jul 24. doi: 10.1111/tpj.12294. [Epub ahead of print]
PMID: 23889683 [PubMed - as supplied by publisher]
Related citations Remove from clipboard
Select item 22865739
2.
Independent FLC mutations as causes of flowering-time variation in Arabidopsis thaliana and Capsella rubella.
Guo YL, Todesco M, Hagmann J, Das S, Weigel D.
Genetics. 2012 Oct;192(2):729-39. doi: 10.1534/genetics.112.143958. Epub 2012 Aug 3.
PMID: 22865739 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations Remove from clipboard
Select item 22837357
3.
Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks.
Hartwig B, James GV, Konrad K, Schneeberger K, Turck F.
Plant Physiol. 2012 Oct;160(2):591-600. doi: 10.1104/pp.112.200311. Epub 2012 Jul 26.
PMID: 22837357 [PubMed - indexed for MEDLINE] Free PMC Article
Related citations Remove from clipboard
Select item 22409706
4.
Synteny-based mapping-by-sequencing enabled by targeted enrichment.
Galvão VC, Nordström KJ, Lanz C, Sulz P, Mathieu J, Posé D, Schmid M, Weigel D, Schneeberger K.
Plant J. 2012 Aug;71(3):517-26. doi: 10.1111/j.1365-313X.2012.04993.x. Epub 2012 May 14.
PMID: 22409706 [PubMed - indexed for MEDLINE]
Related citations Remove from clipboard

这里面第4篇是最早的,这篇文章提到:Mapping-by-sequencing, as implemented in SHOREmap ('SHOREmapping'), is greatly accelerating the identification of causal mutations

SHOREmap源于此文:SHOREmap: simultaneous mapping and mutation identification by deep sequencing.
Schneeberger K, Ossowski S, Lanz C, Juul T, Petersen AH, Nielsen KL, Jørgensen JE, Weigel D, Andersen SU.
Nat Methods. 2009 Aug;6(8):550-1. doi: 10.1038/nmeth0809-550.