今天是放假第一天，写自然基金写的头晕，就把今年发表的论文整理了一下。2010年发表SCI论文25篇，最高影响因子从过去的4分上升到6分，论文数量1年增加了1倍，而且引用次数增加幅度快速提高，2008年第一篇关于氢气的论文引用次数已经达到35次，超过9次的论文数量已经达到9篇，也就是说现在H-index已经到9，对比2007年是1，2008年是3，2009年是5，增加速度是比较快的。保守估计到2011年底H-index应该是12以上。值得注意的是，所有论文中，关于氢气的研究论文达到25篇（09年和10年共发表24篇），占全世界氢气的研究论文总数的30%，顺便产生了几个第一：这个领域本人是发表国际论文最多的作者；我们这个团队是发表论文最多的团队；我们学校是发表论文（30篇）最多的大学；中国是发表论文（35篇）最多的国家等。造成这个高比例的原因是我开展这个工作比较早，我们建立了氢气给药的特殊方法，使许多合作单位需要我们提供帮助而产生了许多合作论文，实际也是抢了许多论文（例如关于老年性痴呆的研究，日本学者比我们早，但我们已经发表2篇论文，他们一直没有发表，估计他们恨的牙疼，从见报后他们马上写信来索取论文全文可见一斑），当然这个比例偏高，我认为理想的比例应该是10%左右，因此将来不能再继续发表低水平论文，否则会引起国际同行的憎恨（已经有这样的感觉了），应该以发表高质量论文为目的，当然最重要的是以解决科学问题为目的。将来继续与各合作单位加强合作，不仅在研究范围上，而且在研究层次上做更好的合作。

 

1.     Liu Y, Xue F, Liu GK, Wang X, Liu Y, Liu WW, Xu L, Sun XJ. Helium preconditioning attenuates hypoxia/ischemia-induced injury in the developing brain. Brain res. 2011. in press

2.     Wang C, Li J, Liu Q, Yang R, Zhang JH, Cao YP, Sun XJ. Hydrogen-rich Saline Reduces Oxidative Stress and Inflammation by Inhibit of JNK and NF-κB Activation in a Rat Model of Amyloid-beta-induced Alzheimer's Disease. Neurosci Lett. 2011 Jan 13. [Epub ahead of print]

3.     Fang Y. Fu XJ, Gu C, Xu P, Wang Y, Yu WR, Sun Q, Sun XJ, Yao M. Hydrogen-Rich Saline Protects against Acute Lung Injury Induced by Extensive Burn in Rat Model. J Burn Care Res.in press

4.     Liu SL, Liu K, Sun Q, Liu WW, Xu WG, Denoble P, Tao HY, Sun XJ. Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. J Biomed Biotechnol. 2011;

5.        Wang F, et al. Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats. J Surg Res.2010; in press

6.     Sun Q, Cai JM,Zhou JR,Tao HY,Zhang JH,Zhang W,Sun XJ.Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. Critical Care medicine. 2010 in press

7.        Chen X, et al. Lactulose: an indirect antioxidant ameliorating inflammatory bowel disease by increasing hydrogen production. Medical Hypotheses 2010

8.        Sun H, Chen L, Zhou W, Hu L, Li L, Tu Q, Chang Y, Liu Q, Sun X, Wu M, Wang H.The Protective Role of Hydrogen -Rich Saline in Experimental Liver Injury in Mice. J Hepatology. 2010; in press

9.        Sun Q, et al. Hydrogen-rich saline provides protection against hyperoxic lung injury J Surg Res.2010; in press

10.    Zhang YF, Sun Q, He B, Xiao J, Wang ZN, Sun XJ. Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. International Journal of Cardiology.2010; in press

11.     Liu SL, Tao HY, Sun Q, Sun XJ. Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury. Medical Hypotheses. 2010; in press

12.     Chen QB et al. Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress and BDNF in spinal cord in a chronic constriction injury rat model. Brain res.2010 in press.

13.    Zheng J, Fang J, Yin YJ, Wang XC, Ren AJ, Bai J, Sun XJ, Yuan WJ, Lin L. Leptin protects cardiomyocytes from serum-deprivation-induced apoptosis by increasing anti-oxidant defence. Clin Exp Pharmacol Physiol, 2010

14.     Fan DF, Liu K, Xu WG, et al. Hyperbaric oxygen preconditioning reduces the incidence of decompression sickness in rats: nitric oxide might be involved. Undersea Hyperb Med. 2010. in press

15.     Huang JL, et al. Through increasing cerebral blood flow acetazolamide aggravates central nervous system oxygen toxicity of rats. Undersea Hyperb Med. 2010. in press

16.     Zheng J, Liu kan`Saturated hydrogen saline protects the lung against oxygen toxicity. Undersea Hyperb Med. 2010

17.     Liu XR, Liu WW, Sun XJ, Liu K, Xu JJ, Lv YH, Yan SK, Zhang WD, Xu WG. Effects of hyperbaric oxygen on uric acid and arachidonic acid: metabolomic study in rats and human. 2010; in press

18.     Zhang P, Liu W, Kang Z, Cai J, Wang Q, Wang S, Zhang JH, Sun XJ*. Sulforaphane Protects Brains against Hypoxic-Ischemic Injury through Induction of Nrf2-Dependent Phase 2 Enzyme. Brain res 2010.

19.     Liu Q, Shen WF, Sun HY, Fan DF, Nakao A, Cai JM i, Yan G, Zhou WP, Shen RX, Yang JM, Sun XJ*. Hydrogen-Rich Saline Protects against Liver Injury in Rats with Obstructive Jaundice. Liver international 2010; in press

20.     Chen CW, Chen QB, Mao YF, Xu SM, Xia CY, Shi XY, Zhang JH, Yuan HB, Sun XJ. Hydrogen-rich saline protects against spinal cord injury in rats.Neurochem Res. 2010;in press

21.     LI J, WANG C, Zhang JH, CAI JM, CAO YP, SUN XJ. Hydrogen-rich Saline Improves Memory Function in a Rat Model of Amyloid-beta-induced Alzheimer’s Disease by Reduction of Oxidative Stress.Brain res. 2010;in press

22.     Chen H, Sun YP, Li Y, Liu WW, Xiang HG, Fan LY, Sun Q, Xu XY, Cai JM, Ruan CP, Su N, Yan RL, Sun XJ, Wang Q. Hydrogen-rich saline ameliorates the severity of L-arginine-induced acute pancreatitis in rats. Biochem Biophys Res Commun.2010; 393: 308-13

23.     Shen MH, Cai JM, Sun Q, He J, Sun XJ, Huo ZL. Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. Med Hypotheses.2010 in press 

24.     Sun Q, Sun Q, Liu Y, Sun XJ, Tao HY. Anti-Apoptotic Effect of Hyperbaric Oxygen Preconditioning on a Rat Model of Myocardial Infarction. J Surg Res.2010; in press

25.     Wang RB, Xu JJ, Xie JX , Kang ZM, Sun XJ, Chen N, Liu L, Xu JJ. Hyperbaric oxygen preconditioning promotes survival of retinal ganglion cells in a rat model of optic nerve crush.  J Neurotrauma. 2010;

 

2009年

26.     Xu X, Wang Z, Li Q, Xiao X, Lian Q, Xu W, Sun X, Tao H, Li R. Endothelial nitric oxide synthase expression is progressively increased in primary cerebral microvascular endothelial cells during hyperbaric oxygen exposure. Oxidative Medicine & Cellular Longevity, 2009, 2(1): 7-13.

27.     Liu W, Zhang J, Ma C, Liu Y, Li R, Sun X, Zhang J, Xu WG*. Dual effects of hyperbaric oxygen on proliferation and cytotoxic T lymphocyte activity of rat splenic lymphocytes. Undersea Hyperb Med. 2009;36(3):155-60.

28.     Chen H, Sun YP, Hu PF, Liu WW, Xiang HG, Li Y,Yan RL, Su N, Ruan CP, Sun XJ, Wang Q.The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. J Surg Res.2009

29.     Sun Q, Kang ZM, Cai JM, Liu WW, Liu Y. Zhang JH, Denoblec PJ, Tao HY, Sun XJ.Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats Exp Biol Med.2009; 234:1212-1219 (if2.2)

30.     Mao YF, Zheng XF, Cai JM, You XM, Deng XM, Zhang JH, Jiang L, Sun XJ. Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. Biochem Biophys Res Commun.2009; 381: 602-605(if2.9)

31.     Zheng XF, Mao YF, Cai JM, Li YH, Liu WW, Sun PL, Zhang JH, Sun XJ, Yuan.HB Hydrogen-Rich Saline Protects against Intestinal Ischemia/Reperfusion Injury in Rats.Free Radical Res.2009; 43(5):478-84. (if2.9)

32.     Li JS, Zhang W, Kang ZM, Liu WW, Ding SJ Zhang JH, Guan YT, Sun XJ. Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by inhibition of apoptosis via mitochondrial way in rat brain. Neuroscience. 2009;159:1309-15..(if3.6)

33.     Xu JJ, Peng ZY, Li RP, Dou TH, Xu WG,Gu GJ, Liu Y, Kang ZM, Tao HY, Zhang JH, Ostrowski RP, Lu J, Sun XJ. Normoxic induction of cerebral HIF-1<alpha> by acetazolamide in rats: role of acidosis. Neurosci lett 2009; 451:374-278. (if2.2)

34.     Matchett GA, Fathali N, Hasegawa Y, Jadhav V, Ostrowski RP, Martin RD, Dorotta IR, Sun XJ, Zhang JH. Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models, Brain Res. 2009;1259:90-7 (if2.5)

35.     Cai JM, Kang ZM, Liu K, Li RP, Zhang JH, Luo X, Sun XJ. Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model. Brain Res. 2009;1256:129-137.(if2.5) 7次

36.     Wang LP, Li WX, Kang ZM, Liu Y, Deng XM, Xu WG, Tao HY, Li RP, Zhang JH, Sun XJ .Hyperbaric Oxygen Preconditioning Attenuates Early Apoptosis after Spinal Cord Ischemia in Rats. J Neurotrauma. 2009; 26 : 55-66. (if3.6)

2008年

37.     Cai JM, Kang ZM, Liu WW, Xu L, Sun Q, Zhang JH, Ohta S, Sun XJ, Xu WG, Tao HY, Li RP. Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model. Neurosci lett. 2008; 441: 167–172. (if2.2) 9次

38.     Gu GJ, Li YP, Peng ZY, Xu JJ, Kang ZM, Xu WG, Tao HY, Ostrowski RP, Zhang JH, Sun XJ. Mechanism of ischemic tolerance induced by hyperbaric oxygen preconditioning involves up-regulation of hypoxia-inducible factor-1a and erythropoietin in rats. J Appl Physiol. 2008; 104(4):1185-1191. (if3.6) 9次

39.     Han CH, Lin L, Zhang WD, Zhang L, Lv SJ, Sun Q, Tao HY, Zhang JH, Sun XJ. Hyperbaric oxygen pretreatment accelerates angiogenesis and alleviates myocardial ischemia in rats. Exp Biol Med.2008; 233: 1448-1453. (if2.2) 2次

40.     Ren P, Kang ZM, Liu Y, Ji H, Sun XJ, Zhang JH. Hyperbaric oxygen preconditioning increases rat liver regeneration by promoting angiogenesis.life sci.2008; 83:236-241.(if 2.5)

41.     Peng ZY, Ren P, Kang ZM, Du J, Lian QL, Liu Y, Zhang JH, Sun XJ. Up-regulated HIF-1 is involved in the hypoxic tolerance induced by hyperbaric oxygen preconditioning.Brain Res. 2008;1212:71-78.( if 2.5)

42.     Li JS, Liu WW, Ding SJ, Xu WG, Guan YT, Zhang JH, Sun XJ. Hyperbaric oxygen preconditioning induces tolerance against brain ischemia-reperfusion injury by upregulation of antioxidant enzymes in rats. Brain Res. 2008;1210:223-229. (if 2.5)

43.     Liu WW, Li JS, Sun XJ, Liu K, Zhang JH, Xu WG, Tao HY. Effect of repetitive hyperbaric oxygen exposures on latency to convulsion and the role of NOS. Brain Res. 2008;1201:128-134.  (if 2.5)

44.     Li Z, Liu WW, Kang ZM, Lv S, Han CH, Sun XJ, Zhang JH. Mechanism of hyperbaric oxygen preconditioning in neonatal hypoxia-ischemia rat model. Brain Res. 2008;1196:151-156. (if 2.5) 5次

45.     Li Q, Guo ML, Xu X, Xiao X, Xu WG, Sun XJ, Tao HY, Li RP. Rapid Decrease of GAD 67 Content Before the Convulsion Induced by Hyperbaric Oxygen Exposure. Neurochem Res. 2008;33(1):185-193. (if2.2)

46.     Sun XJ, Zhang JH. Hydrogen-- an endogenous antioxidant in the body. 第二军医大学学报, 2008; 29: 233-235

2007年

47.     Huang ZX, Kang ZM, Gu GJ, Peng GN, Liu Y, Tao HY, Xu WG, Sun XJ, Zhang JH. Therapeutic effects of hyperbaric oxygen in a rat model of endothelin-1-induced focal cerebral ischemia. Brain Res. 2007;1153:204-213. (if2.5) 3次

48.     Xu WG, Tao HY, Liu Y, Sun XJ, Jiang CL. Immune function in rats following repetitive exposures to 7 ATA air.  Aviat Space Environ Med. 2007;78(4):368-73.

2006年以前

49.     Toft-Hansen H, Buist R, Sun XJ, Schellenberg A, Peeling J, Owens T. Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system. J Immunol. 2006;177(10):7242-7249.

50.  Tang QJ, Tao KZ, Liu Y, Sun XJ, Geng MY, Jiang CL. Immunocytochemical localization of secretory component in Paneth cell secretory granules-rat Paneth cells participate in acquired immunity.J Mol Histol. 2005;36(5):331-335.

51.     Wang YX, Xu WG, Sun XJ, Chen YZ, Liu XY, Tang H, Jiang CL. Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2.J Neuroimmunol. 2004;156(1-2):107-12