Triton X-100 | 曲拉通X-100

MCE 国际站：Triton X-100

中文名：曲拉通X-100

CAS：9002-93-1

品牌：MedChemExpress (MCE)

存储条件：Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：Triton X-100 是一种非变性洗涤剂，可溶解脂质膜。 Triton X-100 通常用于实验室，并应用于制造过程不同阶段的疫苗。 Triton X-100 被列为某些疫苗的赋形剂，包括裂解病毒流感疫苗。 Triton X-100 是一种非离子表面活性剂^[1][2]。

体外：Triton X-100 (0.5%-0.05%，1 小时) 可降低西尼罗河病毒 (WNV) 等经典包膜病毒的感染性[3]。 Triton X-100 (0.19-0.20 mM) 使 HeLa 细胞发生不可逆的膜透化和结构塌陷[4]。 Triton X-100 (0.01%，1 小时) 诱导前列腺和结肠癌细胞系 (PC-3、SW-620 和 HT-29 细胞) 凋亡和坏死，其特征是典型的形态学特征和核小体间 DNA 碎片[5]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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研究领域：Others

作用靶点：Biochemical Assay Reagents

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参考文献：[1]. Herman SM, et al. The hidden allergen: Triton X-100, a derivative of polyethylene glycol. J Allergy Clin Immunol Pract. 2021;9(7):2941. 

[2]. Ghosh R, et al. Unraveling diverse action of triton X-100 and methimazole on lysozyme fibrillation/aggregation: Physicochemical insights. Int J Biol Macromol. 2021;167:736-745. 

[3]. Colavita F, et al. Evaluation of the inactivation effect of Triton X-100 on Ebola virus infectivity. J Clin Virol. 2017 Jan;86:27-30.

[4]. Koley D, et al. Triton X-100 concentration effects on membrane permeability of a single HeLa cell by scanning electrochemical microscopy (SECM). Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16783-7. 

[5]. Borner MM, et alE. The detergent Triton X-100 induces a death pattern in human carcinoma cell lines that resembles cytotoxic lymphocyte-induced apoptosis. FEBS Lett. 1994 Oct 17;353(2):129-32.