|
国际站:Denosumab
CAS:615258-40-7
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性: Denosumab 是一种人单克隆抗体,可结合并抑制 RANKL (TNFSF11) 的受体激活剂。 Denosumab 可以降低脊椎、非脊椎和髋部骨折的风险[1],还具有抗癌活性[2]。
参考文献:[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82.[2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.
Archiver|手机版|科学网 ( 京ICP备07017567号-12 )
GMT+8, 2024-7-17 07:13
Powered by ScienceNet.cn
Copyright © 2007- 中国科学报社