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诺贝尔生理学或医学奖得主，我的预测很准吧！
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我的预测很准吧，哈哈！
我的预测博文：Shinya Yamanaka的论文被引用情况（2010年生理学或医学诺贝尔奖得主预测）
http://blog.sciencenet.cn/home.php?mod=space&uid=280034&do=blog&id=365718
日本京都大学 再生医科学研究所干细胞生物学系教授、美国加州旧金山 心血管疾病研究所 高级调查员以及美国加州大学旧金山分校 解剖学教授 Shinya Yamanaka
获奖原因
因发现干细胞和开发诱导多能干细胞而获奖
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
K Takahashi, S Yamanaka - cell, 2006 - Elsevier
Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about
factors that induce this reprogramming. Here, we demonstrate induction of pluripotent ...
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about
factors that induce this reprogramming. Here, we demonstrate induction of pluripotent ...
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
…, M Narita, T Ichisaka, K Tomoda, S Yamanaka - cell, 2007 - repository.kulib.kyoto-u.ac.jp
抄録: Successful reprogramming of differentiated human somatic cells into a pluripotent state
would allow creation of patient-and disease-specific stem cells. We previously reported
generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from ...
would allow creation of patient-and disease-specific stem cells. We previously reported
generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from ...
Generation of germline-competent induced pluripotent stem cells
K Okita, T Ichisaka, S Yamanaka - Nature, 2007 - nature.com
Abstract We have previously shown that pluripotent stem cells can be induced from mouse
fibroblasts by retroviral introduction of Oct3/4 (also called Pou5f1), Sox2, c-Myc and Klf4, and
subsequent selection for Fbx15 (also called Fbxo15) expression. These induced ...
fibroblasts by retroviral introduction of Oct3/4 (also called Pou5f1), Sox2, c-Myc and Klf4, and
subsequent selection for Fbx15 (also called Fbxo15) expression. These induced ...
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
…, K Okita, Y Mochiduki, N Takizawa, S Yamanaka - Nature …, 2007 - nature.com
Abstract Direct reprogramming of somatic cells provides an opportunity to generate patient-
or disease-specific pluripotent stem cells. Such induced pluripotent stem (iPS) cells were
generated from mouse fibroblasts by retroviral transduction of four transcription factors: ...
or disease-specific pluripotent stem cells. Such induced pluripotent stem (iPS) cells were
generated from mouse fibroblasts by retroviral transduction of four transcription factors: ...
Generation of mouse induced pluripotent stem cells without viral vectors
…, M Nakagawa, H Hyenjong, T Ichisaka, S Yamanaka - Science, 2008 - sciencemag.org
Abstract Induced pluripotent stem (iPS) cells have been generated from mouse and human
somatic cells by introducing Oct3/4 and Sox2 with either Klf4 and c-Myc or Nanog and Lin28
using retroviruses or lentiviruses. Patient-specific iPS cells could be useful in drug ...
somatic cells by introducing Oct3/4 and Sox2 with either Klf4 and c-Myc or Nanog and Lin28
using retroviruses or lentiviruses. Patient-specific iPS cells could be useful in drug ...
Generation of pluripotent stem cells from adult mouse liver and stomach cells
…, K Okita, K Takahashi, T Chiba, S Yamanaka - Science …, 2008 - stke.sciencemag.org
Abstract: Induced pluripotent stem (iPS) cells have been generated from mouse and human
fibroblasts by the retroviral transduction of four transcription factors. However, the cell origins
and molecular mechanisms of iPS cell induction remain elusive. This report describes the ...
fibroblasts by the retroviral transduction of four transcription factors. However, the cell origins
and molecular mechanisms of iPS cell induction remain elusive. This report describes the ...
Strategies and new developments in the generation of patient-specific pluripotent stem cells
S Yamanaka - Cell Stem Cell, 2007 - Elsevier
Generating pluripotent stem cells directly from cells obtained from patients is one of the
ultimate goals in regenerative medicine. Two “reprogramming” strategies for the generation
of pluripotent stem cells from somatic cells have been studied extensively: nuclear transfer ...
ultimate goals in regenerative medicine. Two “reprogramming” strategies for the generation
of pluripotent stem cells from somatic cells have been studied extensively: nuclear transfer ...
[PDF][PDF] The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
…, K Takahashi, M Maruyama, M Maeda, S Yamanaka - cell, 2003 - ccsu.edu
... These data indicate analyses demonstrated that nanog is expressed in ES cells, but not in neural
or hematopoietic stem cells (Ra- ... Positions of the probe and ScaI recognition sites (S) used for
Southern blot were shown. ... scribed (Yamanaka et al., 2000, 1998). ...
or hematopoietic stem cells (Ra- ... Positions of the probe and ScaI recognition sites (S) used for
Southern blot were shown. ... scribed (Yamanaka et al., 2000, 1998). ...
Induction of pluripotent stem cells from fibroblast cultures
K Takahashi, K Okita, M Nakagawa, S Yamanaka - Nature protocols, 2007 - nature.com
Abstract Clinical application of embryonic stem (ES) cells faces difficulties regarding use of
embryos, as well as tissue rejection after implantation. One way to circumvent these issues
is to generate pluripotent stem cells directly from somatic cells. Somatic cells can be ...
embryos, as well as tissue rejection after implantation. One way to circumvent these issues
is to generate pluripotent stem cells directly from somatic cells. Somatic cells can be ...
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
K Takahashi, K Mitsui, S Yamanaka - Nature, 2003 - nature.com
Abstract Embryonic stem (ES) cells are pluripotent cells derived from early mammalian
embryos 1, 2. Their immortality and rapid growth make them attractive sources for stem cell
therapies 3; however, they produce tumours (teratomas) when transplanted, which could ...
embryos 1, 2. Their immortality and rapid growth make them attractive sources for stem cell
therapies 3; however, they produce tumours (teratomas) when transplanted, which could ...
https://wap.sciencenet.cn/blog-280034-620744.html
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