Genomic variants annotating softwares:
(1).ANNOVAR("Annotate Variation");
     http://annovar.openbioinformatics.org/en/latest/
(2).SnpEff("SNP effect");
     http://snpeff.sourceforge.net/
(3).VAAST("Variant Annotation,and Analysis and Search Tool")
     http://www.yandell-lab.org/software/vaast.html
(4).VEP("SNP Effect Predictor")
 http://asia.ensembl.org/info/docs/tools/vep/index.html
(5).AnnTools
 http://anntools.sourceforge.net/
(6).Vcfanno 
 https://github.com/brentp/vcfanno

(注：详细用法请见上述链接)

References
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1.Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR.