近日获悉2023年初正式发表在《Journal of Materials Science & Technology》的一篇论文“AZ31镁合金表面Mg(OH)₂/MAO负载β-环糊精包裹姜黄素涂层的体外降解与多重抗菌机制”（2023, 132: 179-192. DOI：10.1016/j.jmst.2022.04.053）被ESI高被引。

Abstract

It is a challenging task to prepare a coating on Mg alloys for desirable corrosion resistance, good antibacterial ability and biocompatibility. In this research work, an in-situ Mg(OH)(2) coating incorporated with sodium alginate (SA) and beta-cyclodextrin (beta-CD)@curcumin (Cur) was formed on the surface of micro arc oxidation (MAO) coated AZ31 alloy via a low temperature hydrothermal method. Characterization techniques such as X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectrometer (FT-IR) and scanning electron microscope (SEM) were employed to characterize the chemical composition and surface morphology of the coatings. The corrosion protection ability of the coatings was monitored via electrochemical polarization, hydrogen evolution and immersion tests. Photothermal antibacterial ability and cytocompatibility of the coatings were evaluated by plate counting method under the irradiation of 808 nm-near infrared light, in vitro cytotoxicity tests (MIT) and live/dead cell staining. The results indicate that a chelation of the organic molecules led to the formation of a MAO/(beta-CD@Cur)SA-Mg(OH)(2) coating with excellent corrosion protection, multi- antibacterial ability and almost no toxicity to the cells. Especially, the coating provided photothermal performance through the light absorption of Cur, which was encapsulated by beta-CD to improve its bioavailability. SA enhanced the binding force between the drug and the substrate. This novel coating designated the potential application on bioabsorbable magnesium alloys. 

相关介绍，可见科学网博客链接：

镁合金腐蚀研究进展(72)—AZ31镁合金表面Mg(OH)₂ /MAO负载β-环糊精包裹姜黄素涂层的体外降解与多重抗菌机制