小柯机器人

美国国立卫生研究院Hendrikje Nienborg研究团队取得一项新成果。经过不懈努力，他们发现灵长类动物视觉皮层的活动极少受自发运动的调控。2023年10月12日，国际学术期刊《自然-神经科学》发表了这一成果。

研究人员通过同时记录视觉皮层活动以及面部和身体运动，在灵长类动物人类视觉模型猕猴（Macaca mulatta）中测试了这一假说。研究人员还与小鼠研究中使用的类似方法进行了直接比较。

研究人员发现灵长类动物视觉皮层（V1、V2和V3 / V3A）的活动与动物自身的运动有关，但在很大程度上这种调节可以通过运动对视网膜图像的影响来解释，由于视觉输入的变化。这些结果表明，灵长类动物的视觉皮层最少受控于自发运动，这可能反映了物种特异性感觉运动策略。

据悉，生物体在运动时处理感官信息，这种观点被称为具身化。这一观点对于发育神经科学、机器人和系统神经科学很重要。 尚不清楚具身化的调控机制，但在小鼠中观察到全脑神经调控可能是其表现，具体包括在初级视觉皮层中，由与任务无关的自身运动驱动。

附：英文原文

Title: Activity in primate visual cortex is minimally driven by spontaneous movements

Author: Talluri, Bharath Chandra, Kang, Incheol, Lazere, Adam, Quinn, Katrina R., Kaliss, Nicholas, Yates, Jacob L., Butts, Daniel A., Nienborg, Hendrikje

Issue&Volume: 2023-10-12

Abstract: Organisms process sensory information in the context of their own moving bodies, an idea referred to as embodiment. This idea is important for developmental neuroscience, robotics and systems neuroscience. The mechanisms supporting embodiment are unknown, but a manifestation could be the observation in mice of brain-wide neuromodulation, including in the primary visual cortex, driven by task-irrelevant spontaneous body movements. We tested this hypothesis in macaque monkeys (Macaca mulatta), a primate model for human vision, by simultaneously recording visual cortex activity and facial and body movements. We also sought a direct comparison using an analogous approach to those used in mouse studies. Here we found that activity in the primate visual cortex (V1, V2 and V3/V3A) was associated with the animals’ own movements, but this modulation was largely explained by the impact of the movements on the retinal image, that is, by changes in visual input. These results indicate that visual cortex in primates is minimally driven by spontaneous movements and may reflect species-specific sensorimotor strategies.

DOI: 10.1038/s41593-023-01459-5

Source: https://www.nature.com/articles/s41593-023-01459-5

Nature Neuroscience：《自然—神经科学》，创刊于1998年。隶属于施普林格·自然出版集团，最新IF：28.771
官方网址：https://www.nature.com/neuro/
投稿链接：https://mts-nn.nature.com/cgi-bin/main.plex