小柯机器人

2020年10月26日，英国牛津大学Eugene P. Duff、美国华盛顿大学Janine Bijsterbosch等研究人员在《自然—神经科学》杂志发表论文，探讨了功能性脑组织表征的挑战和未来方向。

Title: Challenges and future directions for representations of functional brain organization

Author: Janine Bijsterbosch, Samuel J. Harrison, Saad Jbabdi, Mark Woolrich, Christian Beckmann, Stephen Smith, Eugene P. Duff

Issue&Volume: 2020-10-26

Abstract: A key principle of brain organization is the functional integration of brain regions into interconnected networks. Functional MRI scans acquired at rest offer insights into functional integration via patterns of coherent fluctuations in spontaneous activity, known as functional connectivity. These patterns have been studied intensively and have been linked to cognition and disease. However, the field is fractionated. Diverging analysis approaches have segregated the community into research silos, limiting the replication and clinical translation of findings. A primary source of this fractionation is the diversity of approaches used to reduce complex brain data into a lower-dimensional set of features for analysis and interpretation, which we refer to as brain representations. In this Primer, we provide an overview of different brain representations, lay out the challenges that have led to the fractionation of the field and that continue to form obstacles for convergence, and propose concrete guidelines to unite the field. In this Primer article, Bijsterbosch and colleagues provide an accessible discussion of the challenges faced in analytical representations of functional brain organization and provide clear recommendations to unite a fractionated field.

DOI: 10.1038/s41593-020-00726-z

Source: https://www.nature.com/articles/s41593-020-00726-z

Nature Neuroscience：《自然—神经科学》，创刊于1998年。隶属于施普林格·自然出版集团，最新IF：28.771
官方网址：https://www.nature.com/neuro/
投稿链接：https://mts-nn.nature.com/cgi-bin/main.plex