小柯机器人

实时追踪自报告症状可预测潜在新冠患者
2020-05-12 11:45

英国伦敦国王学院Tim D. Spector、Cristina Menni等研究人员合作通过实时追踪自报告症状来预测了潜在的新冠患者(COVID-19)。这一研究成果于2020年5月11日在线发表在国际学术期刊《自然—医学》上。

研究人员表示,共有2,618,862名参与者在智能手机应用程序中报告了COVID-19的潜在症状。在接受SARS-CoV-2测试的18,401名参与者中,测试结果呈阳性者的气味和味觉下降的比例更高(7,178人中有4,668人;占比65.03%)高于阴性结果者(11,223名参与者中有2,436名;占比21.71%)(比值比=6.74; 95%置信区间=6.31-7.21)。
 
研究人员利用所有应用使用者的数据来建立了模型,在所有报告症状的人(805,753)里预测到140,312(17.42%)的参与者可能患有COVID-19。
 
附:英文原文

Title: Real-time tracking of self-reported symptoms to predict potential COVID-19

Author: Cristina Menni, Ana M. Valdes, Maxim B. Freidin, Carole H. Sudre, Long H. Nguyen, David A. Drew, Sajaysurya Ganesh, Thomas Varsavsky, M. Jorge Cardoso, Julia S. El-Sayed Moustafa, Alessia Visconti, Pirro Hysi, Ruth C. E. Bowyer, Massimo Mangino, Mario Falchi, Jonathan Wolf, Sebastien Ourselin, Andrew T. Chan, Claire J. Steves, Tim D. Spector

Issue&Volume: 2020-05-11

Abstract: A total of 2,618,862 participants reported their potential symptoms of COVID-19 on a smartphone-based app. Among the 18,401 who had undergone a SARS-CoV-2 test, the proportion of participants who reported loss of smell and taste was higher in those with a positive test result (4,668 of 7,178 individuals; 65.03%) than in those with a negative test result (2,436 of 11,223 participants; 21.71%) (odds ratio=6.74; 95% confidence interval=6.31–7.21). A model combining symptoms to predict probable infection was applied to the data from all app users who reported symptoms (805,753) and predicted that 140,312 (17.42%) participants are likely to have COVID-19.

DOI: 10.1038/s41591-020-0916-2

Source: https://www.nature.com/articles/s41591-020-0916-2

Nature Medicine:《自然—医学》,创刊于1995年。隶属于施普林格·自然出版集团,最新IF:87.241
官方网址:https://www.nature.com/nm/
投稿链接:https://mts-nmed.nature.com/cgi-bin/main.plex


本期文章:《自然—医学》:Online/在线发表

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