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中国科学家发现气溶胶中存在新冠病毒RNA
2020-04-28 22:06
来源：小柯机器人

武汉大学蓝柯、陈宇、上海市环境监测中心伏晴艳、复旦大学阚海东、香港中文大学何建辉、香港科技大学宁治等研究人员合作报道了武汉两家医院的SARS-CoV-2空气动力学分析。 2020年4月27日，《自然》在线发表了这一成果。

通过测量2020年2月和2020年3月COVID-19爆发期间武汉两家医院不同区域气溶胶中病毒RNA的含量，研究人员报道了SARS-CoV-2的空气动力学性质。隔离病房和通风良好的病房很低，但是在病房的厕所里升高。除了在两个容易拥挤的地区（可能是由于人群中被感染的携带者）以外，在大多数公共区域中都无法检测到SARS-CoV-2的RNA。
 
研究人员发现，一些医务人员区域最初具有高浓度的病毒RNA，且气溶胶的大小主要分布在亚微米和/或超微米范围，但在执行严格的消毒程序后，这些水平降低至无法检测。尽管研究人员尚未确定在这些医院区域中检测到的病毒的传染性，但认为SARS-CoV-2可能具有通过气溶胶传播的潜力。
 
这些结果表明，室内通风、开放空间、对防护服进行消毒以及对厕所区域的正确使用和消毒可以有效地限制气溶胶中SARS-CoV-2 RNA的浓度。未来的工作应探索气溶胶化病毒的传染性。
 
附：英文原文

Title: Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals

Author: Yuan Liu, Zhi Ning, Yu Chen, Ming Guo, Yingle Liu, Nirmal Kumar Gali, Li Sun, Yusen Duan, Jing Cai, Dane Westerdahl, Xinjin Liu, Ke Xu, Kin-fai Ho, Haidong Kan, Qingyan Fu, Ke Lan

Issue&Volume: 2020-04-27

Abstract: The ongoing COVID-19 outbreak has spread rapidly on a global scale. While the transmission of SARS-CoV-2 via human respiratory droplets and direct contact is clear, the potential for aerosol transmission is poorly understood1–3. This study investigated the aerodynamic nature of SARS-CoV-2 by measuring viral RNA in aerosols in different areas of two Wuhan hospitals during the COVID-19 outbreak in February and March 2020. The concentration of SARS-CoV-2 RNA in aerosols detected in isolation wards and ventilated patient rooms was very low, but it was elevated in the patients’ toilet areas. Levels of airborne SARS-CoV-2 RNA in the majority of public areas was undetectable except in two areas prone to crowding, possibly due to infected carriers in the crowd. We found that some medical staff areas initially had high concentrations of viral RNA with aerosol size distributions showing peaks in submicrometre and/or supermicrometre regions, but these levels were reduced to undetectable levels after implementation of rigorous sanitization procedures. Although we have not established the infectivity of the virus detected in these hospital areas, we propose that SARS-CoV-2 may have the potential to be transmitted via aerosols. Our results indicate that room ventilation, open space, sanitization of protective apparel, and proper use and disinfection of toilet areas can effectively limit the concentration of SARS-CoV-2 RNA in aerosols. Future work should explore the infectivity of aerosolized virus.

DOI: 10.1038/s41586-020-2271-3

Source: https://www.nature.com/articles/s41586-020-2271-3

Nature：《自然》，创刊于1869年。隶属于施普林格·自然出版集团，最新IF：69.504
官方网址：http://www.nature.com/
投稿链接：http://www.nature.com/authors/submit_manuscript.html


本期文章：《自然》：Online/在线发表

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