近日，以色列魏茨曼科学研究所Noam Stern-Ginossar和Ziv Shulman合作总结了RNA修饰N 6-甲基腺苷（m6A）对免疫系统的调节作用。该综述论文于2020年4月13日在线发表于国际一流学术期刊《自然—免疫学》。
Title: The RNA modification N 6 -methyladenosine as a novel regulator of the immune system
Author: Ziv Shulman, Noam Stern-Ginossar
Issue&Volume: 2020-04-13
Abstract: Protection from harmful pathogens depends on activation of the immune system, which relies on tight regulation of gene expression. Recently, the RNA modification N6-methyladenosine (m6A) has been found to play an essential role in such regulation. Here, we summarize newly discovered functions of m6A in controlling various aspects of immunity, including immune recognition, activation of innate and adaptive immune responses, and cell fate decisions. We then discuss some of the current challenges in the field and describe future directions for uncovering the immunological functions of m6A and its mechanisms of action.
DOI: 10.1038/s41590-020-0650-4
Source: https://www.nature.com/articles/s41590-020-0650-4
Nature Immunology：《自然—免疫学》，创刊于2000年。隶属于施普林格·自然出版集团，最新IF：31.25
官方网址：https://www.nature.com/ni/
投稿链接：https://mts-ni.nature.com/cgi-bin/main.plex
本期文章：《自然—免疫学》：Online/在线发表
