小柯机器人

美国国立卫生研究院Afonso C. Silva和Cirong Liu的最新研究，揭示了绒猴脑白质通路详细的三维映射图谱。这一成果2020年1月13日在线发表在国际学术期刊《自然—神经科学》上。

研究人员提供了一种可以详细描述绒猴大脑中白质结构和纤维通路轨迹的数据库。该数据库包括：（1）迄今为止可获得的最高分辨率的扩散加权MRI数据，揭示了先前未描述的白质特征；（2）全面的三维白质图集，描绘了先前图集中遗漏或错误识别的纤维路径；（3）结合弥散加权MRI超声成像和神经元追踪数据揭示的皮质连接的全面纤维通路图。这些数据可以从marmosetbrainmapping.org下载，这将有助于研究大脑的连通性以及灵长类动物大脑中纤维束成像算法的开发。

据介绍，虽然白质在支持神经元交流中的重要性众所周知，但现有出版物并未详细描绘灵长类大脑的特点及其复杂的解剖结构。这主要是由于现有的灵长类动物神经影像数据的空间分辨率不足以完全揭示白质途径。

附：英文原文

Title: A resource for the detailed 3D mapping of white matter pathways in the marmoset brain

Author: Cirong Liu, Frank Q. Ye, John D. Newman, Diego Szczupak, Xiaoguang Tian, Cecil Chern-Chyi Yen, Piotr Majka, Daniel Glen, Marcello G. P. Rosa, David A. Leopold, Afonso C. Silva

Issue&Volume: 2020-01-13

Abstract: While the fundamental importance of the white matter in supporting neuronal communication is well known, existing publications of primate brains do not feature a detailed description of its complex anatomy. The main barrier to achieving this is that existing primate neuroimaging data have insufficient spatial resolution to resolve white matter pathways fully. Here we present a resource that allows detailed descriptions of white matter structures and trajectories of fiber pathways in the marmoset brain. The resource includes: (1) the highest-resolution diffusion-weighted MRI data available to date, which reveal white matter features not previously described; (2) a comprehensive three-dimensional white matter atlas depicting fiber pathways that were either omitted or misidentified in previous atlases; and (3) comprehensive fiber pathway maps of cortical connections combining diffusion-weighted MRI tractography and neuronal tracing data. The resource, which can be downloaded from marmosetbrainmapping.org, will facilitate studies of brain connectivity and the development of tractography algorithms in the primate brain.

DOI: 10.1038/s41593-019-0575-0

Source: https://www.nature.com/articles/s41593-019-0575-0

Nature Neuroscience：《自然—神经科学》，创刊于1998年。隶属于施普林格·自然出版集团，最新IF：28.771
官方网址：https://www.nature.com/neuro/
投稿链接：https://mts-nn.nature.com/cgi-bin/main.plex