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癌症风险与身高关联研究的知识发现
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研究动态
无论男性还是女性，随着身高增高癌症风险都增加。总体上，身高每增高10厘米，女性所有癌症风险增加18%，男性增加11%。对此前文献报道的随身高增高患癌症的风险较高的乳癌和皮肤癌进行了相关性分析，发现身高每增高10厘米，女性乳腺癌风险增加20%，男性乳腺癌因为罕见未做统计。女性皮肤黑色素瘤风险增加32%，男性增加27%。http://tech.sina.com.cn/d/v/2015-11-04/doc-ifxkhcfq1115405.shtml
癌症风险与身高关联研究文献中发现的各类问题和知识点，作为科研选题的参考。
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A-query: Neoplasms RISK C-query: Body Height AND CANCER The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 1307 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 25136 and can be accessed from the start page after you leave this session. There are 362 terms on the current B-list (发现131 基因、遗传学问题are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi
job id # 25136 started Tue Nov 3 21:53:58 2015
Max_citations: 50000
Stoplist: /var/www/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
A_query_raw: Neoplasms RISK Tue Nov 3 21:54:32 2015
A query = Neoplasms RISK started Tue Nov 3 21:54:48 2015
A query resulted in 50000 titles
C_query_raw: Body Height Tue Nov 3 21:55:31 2015
C: Body Height 63094
A: Neoplasms RISK 297448
AC: ( Neoplasms RISK ) AND ( Body Height ) 1307
C_query_raw: Body Height AND CANCER Tue Nov 3 21:57:32 2015
C: Body Height AND CANCER 3372
C_query_raw: Body Height AND CANCER Tue Nov 3 21:57:58 2015
C: Body Height AND CANCER 3372
C_query_raw: Body Height AND CANCER Tue Nov 3 21:59:46 2015
C_query_raw: Body Height AND CANCER Tue Nov 3 21:59:47 2015
C_query_raw: Body Height AND CANCER Tue Nov 3 21:59:48 2015
C: Body Height AND CANCER 3372
C: Body Height AND CANCER 3372
A: Neoplasms RISK 297448
A: Neoplasms RISK 297448
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
C_query_raw: Body Height AND CANCER Tue Nov 3 22:00:24 2015
C: Body Height AND CANCER 3372
A: Neoplasms RISK 297448
A: Neoplasms RISK 297448
C: Body Height AND CANCER 3372
A: Neoplasms RISK 297448
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
C query = Body Height AND CANCER started Tue Nov 3 22:03:48 2015
C query resulted in 3372 titles
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
A: Neoplasms RISK 297448
A AND C query resulted in 1307 titles
8873 B-terms ready on Tue Nov 3 22:07:45 2015
Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
AC: ( Neoplasms RISK ) AND ( Body Height AND CANCER ) 1307
362 B-terms left after filter executed Tue Nov 3 22:10:49 2015
B-list on Tue Nov 3 22:11:25 2015
1 adiponectin
2 fdg
3 psa
4 igfbp-3
5 anti mullerian hormone
6 leptin
7 metabolic syndrome
8 single nucleotide polymorphism
9 nf1
10 fat mass
11 promoter methylation
12 pcos
13 multiple endocrine neoplasia
14 polycystic ovary syndrome
15 aromatase
16 genome wide
17 estrogen receptor alpha
18 ghrelin
19 bone mineral density
20 jazf1
21 adiposity
22 body mass index
23 ezh2
24 wilm tumor
25 leptin receptor
26 cml
27 codon
28 vitamin d receptor
29 inflammatory bowel disease
30 estrogen receptor
31 snp
32 mri
33 codon p53
34 pet
35 progesterone receptor
36 p53 gene
37 androgen receptor
38 allele
39 igf
40 receptor gene
41 cd28
42 glioma
43 gene associated
44 hyperinsulinemia
45 tram
46 alpha fetoprotein
47 hyperparathyroidism
48 codon p53 gene
49 epic
50 obese
http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/view_b_txt.cgi?ID=25136
1974-2015年癌症风险与身高关联研究文献1729篇分布如下：
statistics of 1,729 documents
| | ||
| 123 | ||
Top Years | Publications | |
|---|---|---|
| 2014 | 123 | |
| 2011 | 103 | |
| 2012 | 97 | |
| 2013 | 94 | |
| 2008 | 90 | |
| 2015 | 89 | |
| 2010 | 83 | |
| 2009 | 81 | |
| 2006 | 74 | |
| 2007 | 72 | |
| 2004 | 67 | |
| 2003 | 66 | |
| 2005 | 65 | |
| 2000 | 60 | |
| 2002 | 60 | |
| 2001 | 53 | |
| 1998 | 49 | |
| 1999 | 43 | |
| 1992 | 33 | |
| 1997 | 32 | |
| 123 | ||
| | ||
| 1234 | ||
Top Countries | Publications | |
|---|---|---|
| United States | 706 | |
| United Kingdom | 164 | |
| Sweden | 80 | |
| Norway | 64 | |
| Netherlands | 63 | |
| Germany | 53 | |
| Italy | 53 | |
| Australia | 52 | |
| Canada | 52 | |
| Japan | 51 | |
| France | 47 | |
| Denmark | 37 | |
| China | 32 | |
| South Korea | 24 | |
| Greece | 18 | |
| Spain | 17 | |
| Finland | 16 | |
| Brazil | 15 | |
| Austria | 13 | |
| Taiwan | 13 | |
| 1234 | ||
| | ||
| 123 ...21 | ||
Top Cities | Publications | |
|---|---|---|
| Boston | 142 | |
| Bethesda | 68 | |
| London | 53 | |
| Seattle | 40 | |
| Stockholm | 37 | |
| New York City | 36 | |
| Rockville | 33 | |
| Copenhagen | 28 | |
| Atlanta | 28 | |
| Los Angeles | 27 | |
| Cambridge | 26 | |
| Oslo | 25 | |
| Bristol | 24 | |
| Honolulu | 22 | |
| Houston | 19 | |
| Oxford | 19 | |
| Maastricht | 19 | |
| Chicago | 18 | |
| Brisbane | 18 | |
| Chapel Hill | 18 | |
| 123 ...21 | ||
| | ||
| 123 ...26 | ||
Top Journals | Publications | |
|---|---|---|
| Int J Cancer | 115 | |
| Am J Epidemiol | 111 | |
| Cancer Epidem Biomar | 58 | |
| Cancer Cause Control | 54 | |
| Brit J Cancer | 44 | |
| Cancer Causes Control | 42 | |
| J Natl Cancer I | 32 | |
| Cancer | 30 | |
| Int J Epidemiol | 25 | |
| Arch Intern Med | 22 | |
| Cancer Epidemiol Biomarkers Prev | 21 | |
| Pediatr Blood Cancer | 20 | |
| Eur J Cancer Prev | 20 | |
| Ann Epidemiol | 18 | |
| Br J Cancer | 18 | |
| Breast Cancer Res Tr | 18 | |
| Nutr Cancer | 17 | |
| Am J Clin Nutr | 16 | |
| J Clin Oncol | 16 | |
| Asian Pac J Cancer Prev | 15 | |
| 123 ...26 | ||
| | ||
| 123 ...222 | ||
Top Terms | Publications | |
|---|---|---|
| Humans | 1,612 | |
| Female | 1,329 | |
| Body Mass Index | 1,164 | |
| Risk Factors | 1,160 | |
| Abstracting and Indexing as Topic | 1,099 | |
| Middle Aged | 1,082 | |
| Adult | 1,065 | |
| Women | 884 | |
| Male | 863 | |
| Body Height | 796 | |
| Aged | 789 | |
| Obesity | 707 | |
| Body Weight | 636 | |
| Confidence Intervals | 574 | |
| Breast Neoplasms | 510 | |
| Incidence | 502 | |
| Patients | 486 | |
| Cohort Studies | 452 | |
| Men | 438 | |
| Diagnosis | 436 | |
| 123 ...222 | ||
| | ||
| 123 ...492 | ||
Top Authors | Publications | |
|---|---|---|
| Willett W | 43 | |
| Colditz G | 35 | |
| Stampfer M | 30 | |
| Trichopoulos D | 27 | |
| Manson J | 24 | |
| Tretli S | 21 | |
| Adami H | 20 | |
| La Vecchia C | 18 | |
| Franceschi S | 17 | |
| Brinton L | 16 | |
| Giovannucci E | 15 | |
| Gao Y | 15 | |
| Gunnell D | 15 | |
| Speizer F | 15 | |
| Vatten L | 14 | |
| Bingham S | 14 | |
| Peeters P | 13 | |
| Hennekens C | 13 | |
| Schatzkin A | 12 | |
| Rosner B | 12 | |
| 123 ...492 | ||
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